Syrbe G, Schröder H, Keil E, Jütte A
Klinik für Innere Medizin, Arbeitsgruppe EDV, Friedrich-Schiller-Universität Jena.
Folia Haematol Int Mag Klin Morphol Blutforsch. 1990;117(5):725-9.
Various thrombocyte functions and metabolic criteria were investigated in 309 test persons, among them 198 Patients affected with diabetes mellitus, 67 of type I and 131 of type II as well as 111 healthy control persons. From the variety of these factors an optimal amount was determined by means of the statistical method of multivariance analysis separating both types of diabetes and healthy control persons. In addition to haemoglobin A1 concentration, thrombocyte parameters have been found together with the degree of capillary fragility, adrenalin-induced aggregation, platelet aggregation test and clot retraction, which allow individuals to be assigned diagnostically to various groups of test persons. Thus, thrombocyte functions found in both types of diabetes and normal persons exhibit differences which may contribute to a diagnostic classification.
对309名受测者的多种血小板功能和代谢指标进行了研究，其中包括198名糖尿病患者，67名I型糖尿病患者和131名II型糖尿病患者，以及111名健康对照者。通过多变量分析的统计方法，从这些因素中确定了一个最佳量，从而区分出两种类型的糖尿病患者和健康对照者。除血红蛋白A1浓度外，还发现血小板参数与毛细血管脆性程度、肾上腺素诱导的聚集、血小板聚集试验和血块回缩有关，这些指标可用于将个体诊断性地归入不同的受测者组。因此，在两种类型的糖尿病患者和正常人中发现的血小板功能存在差异，这可能有助于进行诊断分类。
