Parry N M A
Section of Pathology, Department of Biomedical Sciences, Tufts University Cummings School of Veterinary Medicine, 200 Westboro Road, North Grafton, MA 01536, USA.
Vet Pathol. 2006 Nov;43(6):1008-9. doi: 10.1354/vp.43-6-1008.
A perianal mass in a 15-year-old domestic shorthair cat with a history of a firm, painful swelling in the left ventrolateral perianal region was surgically excised and submitted for light microscopic evaluation. Histologically, this was a poorly demarcated, unencapsulated, multilobulated neoplasm that invaded surrounding perirectal skeletal muscle bundles. Lobules were composed of sheets and acinar arrangements of cuboidal to round neoplastic epithelial cells with scant to moderate eosinophilic to amphophilic cytoplasm and a round or oval nucleus with coarse chromatin. Mitotic figures were 2 per 40 x objective field. Acinar lumina sometimes contained eosinophilic proteinaceous material or cell debris. These microscopic features are consistent with anal sac gland carcinoma. This is the second report of this neoplasm in a cat.
一只15岁的家养短毛猫，其左腹外侧肛周区域有一个坚实、疼痛性肿胀的病史，现对其肛周肿物进行手术切除，并送做光镜检查。组织学上，这是一个边界不清、无包膜、多叶状的肿瘤，侵犯周围直肠周围骨骼肌束。小叶由立方形至圆形的肿瘤上皮细胞组成，呈片状和腺泡状排列，胞质嗜酸性至嗜双色性，量少至中等，细胞核圆形或椭圆形，染色质粗糙。每40倍物镜视野有2个有丝分裂象。腺泡腔有时含有嗜酸性蛋白质物质或细胞碎片。这些微观特征与肛囊腺癌一致。这是猫身上该肿瘤的第二例报告。
