van Leeuwen E, Prins J M, Jurriaans S, Boer K, Reiss P, Repping S, van der Veen F
Department of Obstetrics and Gynaecology, Centre for Reproductive Medicine, Academic Medical Centre, Amsterdam, The Netherlands.
Hum Reprod Update. 2007 Mar-Apr;13(2):197-206. doi: 10.1093/humupd/dml052. Epub 2006 Nov 11.
Human immunodeficiency virus type-1 (HIV-1) affects mostly men and women in their reproductive years. For those who have access to highly active antiretroviral therapy (HAART), the course of HIV-1 infection has shifted from a lethal to a chronic disease. As a result of this, many patients with HIV-1 consider having offspring, as do other patients of reproductive age with chronic illnesses. This article summarizes the current knowledge on the presence of HIV in the male and female genital tract, the effects of HIV-1 infection and HAART on male and female fertility and the results of various assisted reproduction techniques (ART) in HIV-1-infected men and women who wish to have offspring.
1型人类免疫缺陷病毒（HIV-1）主要影响处于生育年龄的男性和女性。对于那些能够获得高效抗逆转录病毒疗法（HAART）的人来说，HIV-1感染病程已从致命疾病转变为慢性病。因此，许多HIV-1感染者像其他患有慢性病的育龄患者一样，考虑生育后代。本文总结了目前关于HIV在男性和女性生殖道中的存在情况、HIV-1感染及HAART对男性和女性生育能力的影响，以及希望生育后代的HIV-1感染男性和女性接受各种辅助生殖技术（ART）的结果。
