Elliott Michael R, Arbogast Kristy A, Durbin Dennis R
Department of Biostatistics, University of Michigan School of Public Health, Ann Arbor, Michigan 48109, USA.
J Trauma. 2006 Nov;61(5):1244-8. doi: 10.1097/01.ta.0000195983.48529.0d.
The objective of the study was to determine the constellation of injury patterns in rear-seated, seat-belt-restrained children using data-driven latent class methodology novel to injury prevention research.
A cross-sectional probability sample of rear-seated, belt-restrained children aged 5 to 15 years in crashes was obtained via insurance claims records and a telephone survey. Eight body regions of AIS 2 or greater injury (concussion, nonconcussive head injury, face, chest, abdomen, neck/spine/back, upper extremity, lower extremity) were determined, and a latent class model was fit to determine whether underlying "injury clusters" were present.
A three-class model appears to best fit to observed data: an "abdominal/spine" cluster that contained 11% of the population, a "concussion" cluster that contained 56% of the population, and a residual "mixture" cluster that contained the remaining 33% of the population. When compared with the mixture cluster, the abdomen/spine cluster was associated with 4 to 8 year old children, lap-only belt restraint, frontal impacts, and minivans. The concussion cluster was also more common among 4 to 8 and 9 to 12 year olds, with side or rear impact crashes, and with pickup trucks.
Latent class analysis allows injury clusters to be estimated from the data, not predetermined by the investigator, and suggests that distinct mechanisms of abdominal injury and concussive head injury exist in a population-based sample of children in motor vehicle crashes.
本研究的目的是使用伤害预防研究中新颖的数据驱动潜在类别方法,确定后排座位上系安全带儿童的损伤模式组合。
通过保险理赔记录和电话调查,获取了在车祸中5至15岁后排座位系安全带儿童的横断面概率样本。确定了8个损伤严重程度达到或超过AIS 2级的身体部位(脑震荡、非脑震荡性头部损伤、面部、胸部、腹部、颈部/脊柱/背部、上肢、下肢),并拟合了一个潜在类别模型,以确定是否存在潜在的“损伤簇”。
一个三类模型似乎最适合观察到的数据:一个“腹部/脊柱”簇,占总体的11%;一个“脑震荡”簇,占总体的56%;以及一个剩余的“混合”簇,占总体的33%。与混合簇相比,腹部/脊柱簇与4至8岁儿童、仅使用腰部安全带约束、正面碰撞和小型货车有关。脑震荡簇在4至8岁和9至12岁儿童中也更为常见,与侧面或后部碰撞事故以及皮卡有关。
潜在类别分析允许从数据中估计损伤簇,而不是由研究者预先确定,并表明在机动车碰撞的基于人群的儿童样本中,存在不同的腹部损伤和脑震荡性头部损伤机制。