Magen Eli, Mishal Joseph, Schlesinger Menachem
Medicine B Department, Barzilai Medical Center, Ben Gurion University of Negev, Ashkelon, Israel.
Contact Dermatitis. 2006 Dec;55(6):370-1. doi: 10.1111/j.1600-0536.2006.00878.x.
The TRUE test is a widespread diagnostic tool for initial patch testing of patients with contact dermatitis (CD). From 2002 to 2005, 864 patients with eczema were patch-tested using TRUE test in one Israeli allergology clinic. 547 (63.3%) patients were female and 317 (36.7%) were male. 346 (40%) patients had > or =1 positive patch test reactions. The most common allergens were nickel sulfate for 114 (13.2%) patients, potassium dichromate 111 (12.8%), fragrance mix 59 (6.8%), cobalt chloride 12 (1.4%), ethylenediamine dihydrochloride 11 (1.3%), epoxy resin 11 (1.3%), balsam of Peru 9 (1.0%), carba mix 7 (0.8%), thiomersal 6 (0.7%), wool alcohol 5 (0.6%), black rubber (PPD) mix 5 (0.6%), neomycin 4 (0.5%); Kathon CG, Colophony and Quaternium 15 - each 2 (0.2%), other allergens - each 1 (0.1%). In male patients, carba mix, black rubber (PPD) mix and epoxy resin sensitivity was more frequent, whereas nickel sulfate, fragrance mix, ethylenediamine dihydrochloride and cobalt chloride sensitivity was significantly more frequent in female patients. Our results are in general agreement with previously published reports, excluding the low sensitivity rates to cobalt, which maybe is missed by TRUE test.
TRUE 试验是用于接触性皮炎（CD）患者初始斑贴试验的一种广泛应用的诊断工具。2002年至2005年期间，在以色列一家过敏症诊所，对864例湿疹患者进行了TRUE试验斑贴检测。其中547例（63.3%）为女性，317例（36.7%）为男性。346例（40%）患者斑贴试验反应呈阳性（≥1种变应原）。最常见的变应原是硫酸镍，有114例（13.2%）患者；重铬酸钾111例（12.8%）；香料混合物59例（6.8%）；氯化钴12例（1.4%）；乙二胺二盐酸盐11例（1.3%）；环氧树脂11例（1.3%）；秘鲁香脂9例（1.0%）；卡巴混合物7例（0.8%）；硫柳汞6例（0.7%）；羊毛醇5例（0.6%）；黑橡胶（对苯二胺）混合物5例（0.6%）；新霉素4例（0.5%）；凯松CG、松香和季铵盐15——各2例（0.2%）；其他变应原——各1例（0.1%）。在男性患者中，卡巴混合物、黑橡胶（对苯二胺）混合物和环氧树脂过敏更为常见，而在女性患者中，硫酸镍、香料混合物、乙二胺二盐酸盐和氯化钴过敏明显更为常见。我们的结果与先前发表的报告总体一致，但对钴的低过敏率除外，这可能是TRUE试验遗漏的。
