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纤连蛋白对实验性角膜疾病家兔影响的生化及组织学研究结果

Biochemical and histological findings on the effect of fibronectin in rabbits with experimental corneal disorders.

作者信息

Hiraki S, Hayami H, Numata K, Kubota Y, Kobayashi M, Tanaka S, Karges H E

机构信息

Department of Ophthalmology, School of Medicine, Toyama Medical and Pharmaceutical University, Japan.

出版信息

Arzneimittelforschung. 1990 Dec;40(12):1336-40.

PMID:1710125
Abstract

The effects of purified plasma fibronectin (FN) in corneal disorders were investigated. Histological findings, the levels of ascorbic acid (AA) and glutathione (GSH) in tear fluids were observed sequentially in rabbits with experimental corneal damage and the degree of corneal lesions was observed. The results indicated that healing of the tissue damage was more promoted in the FN group than in the controls and it was suggested that FN promoted the healing of corneal disorders.

摘要

研究了纯化血浆纤连蛋白(FN)在角膜疾病中的作用。对实验性角膜损伤的家兔依次观察组织学结果、泪液中抗坏血酸(AA)和谷胱甘肽(GSH)的水平,并观察角膜病变程度。结果表明,FN组比对照组更能促进组织损伤的愈合,提示FN可促进角膜疾病的愈合。

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Arzneimittelforschung. 1990 Dec;40(12):1336-40.
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