发生于肛周管状乳头状大汗腺腺瘤的原位腺癌。

Adenocarcinoma in situ arising in a tubulopapillary apocrine hidradenoma of the peri-anal region.

作者信息

Obaidat Nidal A, Awamleh Ahlam A, Ghazarian Danny M

机构信息

Department of Laboratory Medicine and Pathobiology, University of Toronto, University Health Network, Toronto General Hospital, EC 11-003, 200 Elizabeth Street, Toronto, ON, Canada.

出版信息

Eur J Dermatol. 2006 Sep-Oct;16(5):576-8.

PMID:17101482

Abstract

We report the case of a 67-year-old woman who presented with a peri-anal skin tag. Histologically, the excised lesion showed features of tubulopapillary apocrine hidradenoma, with an area showing features of carcinoma in situ. The lesion also had papillary and cribriform growth patterns, reminiscent of breast lesions. Similar to vulvar lesions, peri-anal apocrine tumours are believed to arise in mammary like glands (MLGs). To the best of our knowledge, this is the first description of a peri-anal adenocarcinoma in situ arising in a tubulopapillary apocrine hidradenoma. The relationship to MLGs is also discussed.

摘要

我们报告了一例67岁女性患者，其出现肛周皮赘。组织学检查显示，切除的病变具有管状乳头状大汗腺腺瘤的特征，其中一个区域显示原位癌特征。该病变还具有乳头状和筛状生长模式，让人联想到乳腺病变。与外阴病变类似，肛周大汗腺肿瘤被认为起源于类乳腺腺体（MLGs）。据我们所知，这是首次描述在管状乳头状大汗腺腺瘤中发生的肛周原位腺癌。同时也讨论了其与类乳腺腺体的关系。