Koski Renee Rae
College of Pharmacy, Ferris State University, Upper Peninsula Health Education Corporation, 418 West Magnetic Street, Marquette, MI 49855, USA.
Diabetes Educ. 2006 Nov-Dec;32(6):869-76. doi: 10.1177/0145721706294260.
This article gives a practical review of the pharmacology, clinical efficacy, safety, dosing, cost, and place in therapy for oral antihyperglycemic agents used in the treatment of type 2 diabetes mellitus. There are 5 classes of oral antihyperglycemic agents available in the United States: sulfonylurea secretagogues, biguanides, alpha-glucosidase inhibitors, thiazolidinediones, and nonsulfonylurea secretagogues. These agents have distinct characteristics that help in their selection for the treatment of type 2 diabetes.
本文对用于治疗2型糖尿病的口服降糖药的药理学、临床疗效、安全性、给药剂量、成本及治疗地位进行了实用性综述。在美国有五类口服降糖药：磺脲类促泌剂、双胍类、α-葡萄糖苷酶抑制剂、噻唑烷二酮类和非磺脲类促泌剂。这些药物具有不同特点，有助于在治疗2型糖尿病时进行选择。
