巨细胞病毒相关性结肠炎在一名免疫功能正常的患者中引发腹泻。
Cytomegalovirus-associated colitis causing diarrhea in an immunocompetent patient.
作者信息
Carter Dan, Olchovsky David, Pokroy Russell, Ezra David
机构信息
Internal Medicine A, Sheba Medical Center, Tel Hashomer, Israel.
出版信息
World J Gastroenterol. 2006 Nov 14;12(42):6898-9. doi: 10.3748/wjg.v12.i42.6898.
Abstract
Cytomegalovirus (CMV) colitis rarely occurs in immunocompetent patients. We report a case of disabling and life threatening diarrhea in an immunocompetent elderly woman due to CMV colitis. The diagnosis of CMV was based on histological examination of tissues biopsied at colonoscopy, positive CMV antigen and high CMV-IgM titer in peripheral blood samples and a good response to systemic gancyclovir treatment. We conclude that CMV should be considered in the differential diagnosis of colitis in elderly immunocompetent patients.
摘要
巨细胞病毒（CMV）结肠炎在免疫功能正常的患者中很少见。我们报告一例免疫功能正常的老年女性因CMV结肠炎出现致残性且危及生命的腹泻病例。CMV的诊断基于结肠镜检查时活检组织的组织学检查、外周血样本中CMV抗原阳性和CMV-IgM高滴度以及对全身更昔洛韦治疗的良好反应。我们得出结论，在免疫功能正常的老年患者结肠炎的鉴别诊断中应考虑CMV。
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