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餐后血脂异常和残余脂蛋白

Postprandial lipemia and remnant lipoproteins.

作者信息

Cohn Jeffrey S

机构信息

Nutrition and Metabolism Group, Heart Research Institute, 114 Pyrmont Bridge Road, Camperdown, NSW 2050, Australia.

出版信息

Clin Lab Med. 2006 Dec;26(4):773-86. doi: 10.1016/j.cll.2006.07.003.

Abstract

Increased postprandial lipemia or elevated levels of triglyceride-rich remnant lipoproteins in fasting plasma are associated with increased risk of coronary artery disease. Despite many studies showing that postprandial triglyceride-rich lipoproteins play a central role in the pathogenesis of atherosclerosis, suitably standardized methods to measure postprandial lipemia or remnant lipoproteins in the clinical setting are lacking. This approach for cardiovascular risk assessment is confined to research laboratories and for the time being is not a standard procedure in clinical practice.

摘要

餐后血脂升高或空腹血浆中富含甘油三酯的残余脂蛋白水平升高与冠状动脉疾病风险增加相关。尽管许多研究表明,餐后富含甘油三酯的脂蛋白在动脉粥样硬化发病机制中起核心作用,但在临床环境中缺乏适当标准化的方法来测量餐后血脂或残余脂蛋白。这种心血管风险评估方法仅限于研究实验室,目前在临床实践中并非标准程序。

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