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基于等离子射频的椎间盘切除术治疗颈椎间盘突出症:可行性、安全性及初步临床结果

Plasma radio-frequency-based diskectomy for treatment of cervical herniated nucleus pulposus: feasibility, safety, and preliminary clinical results.

作者信息

Bonaldi G, Baruzzi F, Facchinetti A, Fachinetti P, Lunghi S

机构信息

Department of Neuroradiology, Ospedali Riuniti, Bergamo, Italy.

出版信息

AJNR Am J Neuroradiol. 2006 Nov-Dec;27(10):2104-11.

Abstract

BACKGROUND AND PURPOSE

Several techniques, including chymopapain, mechanical aspiration, laser-based disk decompression, and endoscopic keyhole surgery, have been proposed as minimally invasive alternatives to fusion for treating cervical disk herniation, though none has gained wide acceptance. The purpose of this study was to assess feasibility, safety, and preliminary clinical results of percutaneous plasma-mediated radio-frequency-based diskectomy for cervical disk herniation.

METHODS

Patients (N = 55) with cervical soft disk protrusion were treated over a 29-month period. They had radicular pain; 3 patients also had moderate myelopathy. The procedure was performed with the Perc-DC SpineWand by using an anterior approach. Most cases were conducted with local anesthetic on an outpatient basis. Clinical outcomes were graded by using the Macnab criteria.

RESULTS

At 2 months, outcomes were good or excellent in 44/55 (80%) patients; the success rate was similar at 6 months, when 44 (85%) patients (n = 52/55) had good or excellent results. One clinically relevant complication (infectious diskitis) occurred within the first month postprocedure and was successfully treated. One technical complication (in situ rupture of the device tip) was observed; however, the patient remained asymptomatic during the 2-year follow-up. The 3 patients with clinical myelopathy experienced regression of cord compression symptoms; MR imaging in 2 patients showed morphologic evidence of reduction of cord compression.

CONCLUSIONS

Plasma radio-frequency-based diskectomy in the cervical spine appears to be a minimally invasive low-risk approach, which is easy to perform, associated with only minimal discomfort to the patient, and effective in the short term.

摘要

背景与目的

已经提出了多种技术,包括木瓜凝乳蛋白酶、机械抽吸、激光椎间盘减压和内镜锁孔手术,作为融合术的微创替代方法来治疗颈椎间盘突出症,不过这些技术均未获得广泛认可。本研究的目的是评估经皮等离子介导射频椎间盘切除术治疗颈椎间盘突出症的可行性、安全性和初步临床结果。

方法

在29个月期间对55例颈椎软性椎间盘突出患者进行了治疗。他们有神经根性疼痛;3例患者还伴有中度脊髓病。使用Perc-DC脊柱棒通过前路进行手术。大多数病例在门诊采用局部麻醉进行。使用Macnab标准对临床结果进行分级。

结果

在2个月时,44/55(80%)的患者结果为良好或优秀;在6个月时成功率相似,此时44例(85%)患者(n = 52/55)结果为良好或优秀。术后第一个月内发生了1例临床相关并发症(感染性椎间盘炎),并成功治愈。观察到1例技术并发症(设备尖端原位破裂);然而,该患者在2年随访期间无症状。3例临床脊髓病患者的脊髓压迫症状有所缓解;2例患者的磁共振成像显示脊髓压迫减轻的形态学证据。

结论

颈椎等离子射频椎间盘切除术似乎是一种微创、低风险的方法,操作简便,患者仅有轻微不适,且短期内有效。

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