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使用尸体椎间盘评估增强型功率等离子体发生器的切除效率和安全性。

Evaluation of the resection efficiency and safety of an enhanced power plasma generator using cadaveric intervertebral discs.

作者信息

Hong Youngki, Yoon Sung-Young, Sohn Sangho, Kim Nack Hwan, Kim Yushin, Lee Sangheon

机构信息

Department of Sports Health and Rehabilitation, College of Health Science, Cheongju University, 298, Daesung-Ro, Sangdang-Gu, 360-764 Cheongju, South Korea.

Samsung Mechatronics R&D Center, SEC, 1, Samsunggjeonja-ro, Hwaseoung-si, Gyeonggi-do South Korea.

出版信息

Biomed Eng Lett. 2022 Dec 19;13(1):57-64. doi: 10.1007/s13534-022-00253-9. eCollection 2023 Feb.

Abstract

Plasma energy has been used to provide minimally invasive interventional treatment for spinal problems. However, this procedure has been used for limited indications mainly because of its small resection range. To overcome this problem, we designed the enhanced power plasma device. This device seeks to maximize the resection area by modifying the electrode arrangement and enhancing the maximum electric power. The purpose of this study is to assess the efficiency and safety of this newly designed plasma generator, a device for percutaneous disc decompression. We performed an intradiscal procedure on 7 fresh human cadaver lumbar spine specimens using the enhanced power plasma under C-arm fluoroscopic guidance at various voltages. As a result, the volume of the removed area was proportional to the applied magnitude of the electric power level. In particular, under the high-power level condition after 500 s treatment, nearly the entire nucleus pulposus was eliminated. The generated plasma density also tends to grow along with the given electric power. The highest level of temperature rise did not exceed the level that would lead to degeneration in the collagen tissue of the intervertebral disc. Histopathologic examination also demonstrated that there was no thermal damage to the surrounding neural tissues. In conclusion, we speculate that the concepts of this newly designed enhanced plasma generator could be applied to remove huge disc materials without thermal or structural damage to the adjacent target tissues in future spine clinics.

摘要

等离子体能量已被用于为脊柱问题提供微创介入治疗。然而,该手术的适应症有限,主要是因为其切除范围较小。为克服这一问题,我们设计了增强功率等离子体装置。该装置旨在通过修改电极排列和提高最大电功率来最大化切除面积。本研究的目的是评估这种新设计的等离子体发生器(一种用于经皮椎间盘减压的装置)的效率和安全性。我们在C形臂荧光透视引导下,使用增强功率等离子体对7个新鲜人类尸体腰椎标本在不同电压下进行了椎间盘内手术。结果,切除区域的体积与施加的电功率水平大小成正比。特别是在500秒治疗后的高功率水平条件下,几乎整个髓核都被清除。产生的等离子体密度也倾向于随着给定的电功率而增加。最高温度上升水平未超过会导致椎间盘胶原组织退变的水平。组织病理学检查还表明,周围神经组织没有热损伤。总之,我们推测这种新设计的增强等离子体发生器的理念可应用于未来脊柱临床中去除巨大的椎间盘物质,而不会对相邻目标组织造成热损伤或结构损伤。

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