Nowakowska Zdzisława
Department of Chemistry, Adam Mickiewicz University, Grunwaldzka, Poznań, Poland.
Eur J Med Chem. 2007 Feb;42(2):125-37. doi: 10.1016/j.ejmech.2006.09.019. Epub 2006 Nov 15.
Chalcones, considered as the precursors of flavonoids and isoflavonoids, are abundant in edible plants, and have also been shown to display a diverse array of pharmacological activities. The purpose of this review is to provide an overview of the pharmacological activity of synthetic and naturally occurring chalcones. This review is complementary to earlier reviews and covers more recent reports of antimicrobial activity of chalcones (antibacterial and antifungal), as well as antileishmanial, antimalarial, antiviral and anti-inflammatory activities of these compounds.
查耳酮被认为是黄酮类化合物和异黄酮类化合物的前体，在可食用植物中含量丰富，并且还显示出多种药理活性。本综述的目的是概述合成查耳酮和天然查耳酮的药理活性。本综述是对早期综述的补充，涵盖了查耳酮抗菌活性（抗菌和抗真菌）的最新报道，以及这些化合物的抗利什曼原虫、抗疟疾、抗病毒和抗炎活性。
