Isaac J R, Sim E K, Ngoi S S, Goh P M
Department of Surgery, National University Hospital, Singapore.
Am Surg. 1991 Apr;57(4):245-9.
Patients with carcinoma of the esophagus continue to present late when their tumors are inoperable. This makes palliation of their dysphagia the main therapeutic aim. The Nd-YAG laser has been used in our department to treat dysphagia resulting from cancer of the esophagus since 1986. Our rapid, one-stage cannulation technique using the Nd-YAG laser in both contact and noncontact modes was applied to 35 cases of carcinoma of the esophagus with the aim of achieving rapid and safe palliation of dysphagia. During the treatment we aimed not to coagulate the tumor and await sloughing, but to vaporize the tumor and ablate as much as possible in a single session. In this way there was less need for repeat sessions to create an adequate lumen. In a small number of patients (9) who had tight strictures with no visible lumen, a pre-laser dilation was required to allow visualization of the lumen and tumor vaporization. For nondilated patients (26) we achieved a 15-mm lumen in an average of 1.6 sessions, and in the dilated patients (9) this was achieved in one session in all patients. Functional improvement occurred in 28 patients (80%). There were four minor complications and no mortality associated with the procedure.
食管癌患者就诊时肿瘤往往已无法手术切除,多为晚期。因此,缓解吞咽困难成为主要治疗目标。自1986年起,我院使用钕钇铝石榴石激光治疗食管癌所致吞咽困难。我们采用快速一步插管技术,将钕钇铝石榴石激光以接触和非接触模式应用于35例食管癌患者,旨在快速、安全地缓解吞咽困难。治疗过程中,我们的目标不是凝固肿瘤并等待其脱落,而是汽化肿瘤并在单次治疗中尽可能多地消融。这样一来,就减少了为形成足够管腔而进行重复治疗的必要性。少数患者(9例)存在严重狭窄且无可见管腔,需要在激光治疗前进行扩张,以便能够看到管腔并汽化肿瘤。对于未扩张的患者(26例),平均1.6次治疗后管腔达到15毫米,而对于已扩张的患者(9例),所有患者均在一次治疗后达到这一效果。28例患者(80%)功能得到改善。该操作有4例轻微并发症,无死亡病例。