Chen Hsiu Ling, Su Huei Jen, Lee Ching Chang
Department of Industrial Safety and Health, Hung Kuang University, Taichung, Taiwan.
Environ Int. 2007 Feb;33(2):265-71. doi: 10.1016/j.envint.2006.09.019. Epub 2006 Nov 17.
Age and gender are related to human dietary habits, which affect serum levels of dioxin-like compounds via body fat content. This study examined whether different dietary patterns and body fat content were associated with serum polychlorinated dibenzo-p-dioxins and dibenzofurans (PCDD/F) concentrations for different age groups of Taiwanese subjects. In total, 1165 volunteers completed a semi-quantitative food-consumption frequency questionnaire for serum PCDD/Fs analysis. In the elderly (age, >45 years), a significant positive multivariate-adjusted association was identified between serum PCDD/F levels and sea fish intake. Additionally, consumption of tofu was negatively correlated with serum PCDD/F levels. This study also found a negative correlation between tofu intake and body fat content in the elderly. It seems that when elderly people ingested considerable amounts of soybean protein, such as tofu, they typically had low serum PCDD/Fs levels in relation to reduced body fat content and induction of metabolic enzymes. The relationship between tofu intake, metabolic enzymes, and serum PCDD/F accumulations warrants further investigated previously to recommend how to prevent PCDD/F accumulations via intake of soybean products.
年龄和性别与人类饮食习惯相关，而饮食习惯通过体脂含量影响血清中二噁英类化合物的水平。本研究调查了不同的饮食模式和体脂含量是否与台湾不同年龄组受试者血清多氯二苯并对二噁英和多氯二苯并呋喃（PCDD/F）浓度相关。共有1165名志愿者完成了一份半定量食物消费频率问卷，用于血清PCDD/F分析。在老年人（年龄>45岁）中，血清PCDD/F水平与海鱼摄入量之间存在显著的多变量调整后正相关。此外，豆腐的摄入量与血清PCDD/F水平呈负相关。本研究还发现老年人豆腐摄入量与体脂含量之间存在负相关。似乎当老年人摄入大量大豆蛋白，如豆腐时，他们的血清PCDD/F水平通常较低，这与体脂含量降低和代谢酶的诱导有关。豆腐摄入量、代谢酶和血清PCDD/F积累之间的关系值得进一步研究，以便此前能建议如何通过摄入大豆制品来预防PCDD/F积累。
