Khandelwal N, Agarwal Ajay, Kochhar Rohit, Bapuraj J R, Singh Paramjeet, Prabhakar S, Suri S
Department of Radiodiagnosis and Imaging, Postgraduate Institute of Medical Education and Research, Chandigarh 160012, India.
AJR Am J Roentgenol. 2006 Dec;187(6):1637-43. doi: 10.2214/AJR.05.1249.
The purpose of this study was to compare cerebral CT venography with MR venography and determine the reliability of CT venography in the diagnosis of cerebral sinovenous thrombosis.
Fifty patients who were clinically suspected of having cerebral sinovenous thrombosis, irrespective of age and sex, underwent cerebral CT venography and MR venography. Projection venograms were displayed using maximum-intensity-projection images for both CT venography and MR venography. The CT venograms were also displayed using the integral algorithm, which depicts the average intensity value of the first five voxels deep in relation to the model surface that is nearest the viewer, allowing direct visualization of the thrombus in the sinuses. All CT venograms and MR venograms were independently evaluated by experienced neuroradiologists.
Of these 50 patients, 30 patients were diagnosed as having cerebral sinovenous thrombosis on both CT venography and MR venography. The total numbers of sinuses involved were 81 and 77 (CT venography and MR venography). When MR venography was used as the gold standard, CT venography was found to have both a sensitivity and a specificity of 75-100%, depending on the sinus and vein involved.
CT venography is as accurate as MR venography for diagnosing cerebral sinovenous thrombosis.
本研究旨在比较脑CT静脉造影与磁共振静脉造影，并确定CT静脉造影在诊断脑静脉窦血栓形成中的可靠性。
50例临床怀疑患有脑静脉窦血栓形成的患者，不分年龄和性别，均接受了脑CT静脉造影和磁共振静脉造影。CT静脉造影和磁共振静脉造影均使用最大密度投影图像显示投影静脉造影。CT静脉造影还使用积分算法显示，该算法描绘了相对于最靠近观察者的模型表面深处前五个体素的平均强度值，从而可以直接观察到静脉窦内的血栓。所有CT静脉造影和磁共振静脉造影均由经验丰富的神经放射科医生独立评估。
在这50例患者中，30例患者在CT静脉造影和磁共振静脉造影上均被诊断为患有脑静脉窦血栓形成。受累静脉窦总数分别为81个和77个（CT静脉造影和磁共振静脉造影）。以磁共振静脉造影作为金标准时，发现CT静脉造影的敏感性和特异性为75%-100%，具体取决于受累的静脉窦和静脉。
CT静脉造影在诊断脑静脉窦血栓形成方面与磁共振静脉造影一样准确。
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