Meuwese-Jongejeugd Anneke, Vink Marianne, van Zanten Bert, Verschuure Hans, Eichhorn Edwin, Koopman Dick, Bernsen Roos, Evenhuis Heleen
Erasmus University Medical Center, Rotterdam, The Netherlands.
Int J Audiol. 2006 Nov;45(11):660-9. doi: 10.1080/14992020600920812.
A cross-sectional epidemiological study on prevalence of hearing loss was carried out in an age- and Down's syndrome- stratified random sample of 1598 persons drawn from a base population of 9012 persons, representative of the Dutch adult population of intellectual disability (ID) service users. The re-weighted population prevalence is 30.3% (95% confidence interval [CI]: 27.7-33.0%). Subgroup prevalences range from 7.5% (95% confidence interval [CI]: 3.6-13.3) in the subgroup aged 18-30 years with ID by other causes than Down's syndrome, up to 100% (95% CI: 79.4-100%) in adults over 60 years of age with Down's syndrome. Down's syndrome (OR 5.18, 95% CI 3.80-7.07) and age were confirmed to be risk factors. Age-related increase in prevalence in persons with Down's syndrome appears to occur approximately three decades earlier, and in persons with ID by other causes approximately one decade earlier than in the general population.
针对听力损失患病率开展了一项横断面流行病学研究，该研究在从9012人的基础人群中抽取的1598人组成的年龄和唐氏综合征分层随机样本中进行，该基础人群代表荷兰成年智力残疾（ID）服务使用者。重新加权后的总体患病率为30.3%（95%置信区间[CI]：27.7 - 33.0%）。亚组患病率范围从唐氏综合征以外其他原因导致ID的18 - 30岁亚组中的7.5%（95%置信区间[CI]：3.6 - 13.3），到唐氏综合征60岁以上成年人中的100%（95% CI：79.4 - 100%）。唐氏综合征（比值比5.18，95% CI 3.80 - 7.07）和年龄被确认为风险因素。唐氏综合征患者中与年龄相关的患病率增加似乎比一般人群早约三十年出现，其他原因导致ID的患者中则比一般人群早约十年出现。
