Nishikawa H, Manek S, Green C J
Department of Plastic Surgical Research, Mount Vernon Hospital, Northwood, Middlesex.
Br J Plast Surg. 1991 May-Jun;44(4):295-8. doi: 10.1016/0007-1226(91)90075-u.
Neovascularisation from the bed can result in the partial survival of failing rat groin flaps. This can interfere with the interpretation of pharmacological augmentation and ischaemia experiments. We describe the development of a modified rat groin flap which utilises the inguinal fat pad to diminish the effects of the bed on the skin component of the flap. The behaviour of this model is compared to that of standard rat groin flaps and flaps which have had polythene sheeting placed under them.
来自创面床的新生血管形成可导致衰竭的大鼠腹股沟皮瓣部分存活。这可能会干扰药理学增强和缺血实验的解读。我们描述了一种改良大鼠腹股沟皮瓣的研制,该皮瓣利用腹股沟脂肪垫来减少创面床对皮瓣皮肤部分的影响。将该模型的行为与标准大鼠腹股沟皮瓣以及在其下方放置聚乙烯薄膜的皮瓣的行为进行比较。