Kurnik B R, Singer F, Groh W C
Department of Medicine, UMDNJ/Robert Wood Johnson Medical School, Camden.
Am J Med Sci. 1991 Jul;302(1):28-30. doi: 10.1097/00000441-199107000-00007.
Acute renal failure is an infrequent adverse reaction following the administration of dextran-40. We report a case of anuric acute renal failure in a 59-year-old female following the administration of 90 gm of dextran-40 and radiocontrast. An increased risk secondary to radiocontrast-induced ischemia is discussed in relationship to the pathogenesis of the dextran-induced acute renal failure. In addition, plasmapheresis is demonstrated to be of potential therapeutic benefit.
急性肾衰竭是给予右旋糖酐40后罕见的不良反应。我们报告一例59岁女性在输注90克右旋糖酐40及使用放射性造影剂后出现无尿性急性肾衰竭的病例。结合右旋糖酐所致急性肾衰竭的发病机制，讨论了放射性造影剂诱发缺血导致风险增加的情况。此外，已证明血浆置换可能具有治疗益处。
