Paavilainen P, Alho K, Reinikainen K, Sams M, Näätänen R
Department of Psychology, University of Helsinki, Finland.
Electroencephalogr Clin Neurophysiol. 1991 Jun;78(6):466-79. doi: 10.1016/0013-4694(91)90064-b.
Auditory stimulus blocks were presented to 10 reading subjects. Each block consisted of 2 types of stimulus, standard (P = 90%) and deviant (P = 10%), delivered in a random order with short constant inter-stimulus intervals. The standard stimuli were 600 Hz. 80 dB SPL 50 msec sine wave bursts. In different blocks, the deviant stimuli differed from the standards either in frequency (650 Hz), intensity (70 dB) or duration (20 msec). Left- and right-ear stimulations were used in separate blocks. Event-related brain potentials (ERPs) were recorded with 16 electrodes over both hemispheres. All the different types of deviant stimuli elicited an ERP component called the mismatch negativity (MMN). The MMN was larger over the right hemisphere irrespective of the ear stimulated whereas the N1 component, elicited by both standards and deviants, was larger over the hemisphere contralateral to the ear stimulated. The results provide further evidence for the view that the MMN reflects a neural mismatch process with a memory trace which automatically codes the physical features of the repetitive stimuli.
对10名阅读受试者施加听觉刺激组块。每个组块由两种类型的刺激组成，标准刺激（概率P = 90%）和偏差刺激（概率P = 10%），以随机顺序呈现，刺激间隔短暂且恒定。标准刺激为600赫兹、80分贝声压级、50毫秒的正弦波脉冲串。在不同组块中，偏差刺激在频率（650赫兹）、强度（70分贝）或持续时间（20毫秒）方面与标准刺激不同。左耳和右耳刺激分别在不同组块中进行。使用16个电极记录双侧半球的事件相关脑电位（ERP）。所有不同类型的偏差刺激均引发一种称为失配负波（MMN）的ERP成分。无论刺激的是哪只耳朵，MMN在右半球上更大，而由标准刺激和偏差刺激均引发的N1成分，在受刺激耳朵对侧的半球上更大。这些结果为以下观点提供了进一步的证据，即MMN反映了一个具有记忆痕迹的神经失配过程，该记忆痕迹自动编码重复刺激的物理特征。
