Watelet Jean-Baptiste, Evrard Anne-Sophie, Lawson Georges, Bonte Katrien, Remacle Marc, Van Cauwenberge Paul, Vermeersch Hubert
Department of Otorhinolaryngology and Head & Neck Surgery, Ghent University Hospital, Ghent, Belgium.
Eur Arch Otorhinolaryngol. 2007 May;264(5):505-7. doi: 10.1007/s00405-006-0207-7. Epub 2006 Nov 24.
Compared to herpes zoster oticus, varicella zoster virus (VZV) reactivations in immunocompetent patients are rare in laryngeal region. Usually, associated vocal cord paralyses are reported. Herein is a case report of a patient with laryngeal zoster without any associated motor disorders. An attempt is made to assign the distribution of mucosal eruptions to the appropriate neuroanatomical structures. A description of the serological course of VZV IgM and IgG are provided. Vesicles were found on the left sensory distribution areas of the superior laryngeal nerve. VZV IgM and IgG antibodies reached their peak 1 month after initial symptoms. Attentive follow-up and no antiviral therapy were advocated because of the absence of any immune deficiency or endoscopic suspicion of malignancy. In this case of VZV reactivation in the sensitive area of the superior laryngeal nerve, serological profiles of VZV IgM and IgG were profoundly modified up to the fourth month.
与耳带状疱疹相比,免疫功能正常的患者中,水痘带状疱疹病毒(VZV)在喉部区域的再激活很少见。通常会报告伴有声带麻痹。本文报告一例喉带状疱疹患者,无任何相关运动障碍。尝试将黏膜疹的分布归因于适当的神经解剖结构。提供了VZV IgM和IgG的血清学病程描述。在上喉神经的左侧感觉分布区域发现了水疱。VZV IgM和IgG抗体在初始症状出现1个月后达到峰值。由于没有任何免疫缺陷或内镜检查怀疑恶性肿瘤,主张进行密切随访且不进行抗病毒治疗。在这例上喉神经敏感区域的VZV再激活病例中,VZV IgM和IgG的血清学特征在第四个月前发生了深刻变化。