Baia L, Baia M, Popp J, Astilean S
Faculty of Physics, Babes-Bolyai University, M. Kogalniceanu 1, 400084 Cluj-Napoca, Romania.
J Phys Chem B. 2006 Nov 30;110(47):23982-6. doi: 10.1021/jp064458k.
Gold nanostructured films of various thicknesses (15, 30, and 60 nm) are deposited over regular arrays of polystyrene nanospheres in an attempt to evaluate their potential as SERS-active substrates. Atomic force microscopy is used to topographically characterize the substrates as well as to ensure the thickness of the deposited gold films. The optical response of the prepared substrates recommends their use in SERS experiments with multiple laser lines from visible and NIR spectral domains. The assessment of the substrates' SERS activity is performed by using the 532, 633, and 830 nm excitation lines and different average enhancement factor (EF) values are obtained depending on the film thickness and employed laser line. The 60 nm gold nanostructured film generates the greatest local electromagnetic field confinement under NIR excitation and consequently gives rise to maximum SERS enhancement. The large tunability of surface plasmon excitation combined with the advantage of relatively high exhibited average EF values obtained under NIR excitation recommends these substrates as outstanding candidates for upcoming investigations of biological relevant molecules.
将不同厚度（15、30和60纳米）的金纳米结构薄膜沉积在聚苯乙烯纳米球的规则阵列上，以评估其作为表面增强拉曼散射（SERS）活性基底的潜力。原子力显微镜用于对基底进行形貌表征，并确保沉积金膜的厚度。所制备基底的光学响应表明它们可用于可见光和近红外光谱域的多条激光线的SERS实验。通过使用532、633和830纳米的激发线对基底的SERS活性进行评估，根据膜厚度和所使用的激光线获得不同的平均增强因子（EF）值。60纳米的金纳米结构薄膜在近红外激发下产生最大的局部电磁场限制，因此产生最大的SERS增强。表面等离子体激元激发的大可调性与近红外激发下获得的相对较高的平均EF值的优势相结合，表明这些基底是未来生物相关分子研究的优秀候选者。
