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老年人心力衰竭的流行病学、病理生理学及预后

Epidemiology, pathophysiology, and prognosis of heart failure in the elderly.

作者信息

Thomas Sabu, Rich Michael W

机构信息

Washington University School of Medicine, 660 South Euclid Avenue, Campus Box 8086, St. Louis, MO 63110, USA.

出版信息

Clin Geriatr Med. 2007 Feb;23(1):1-10. doi: 10.1016/j.cger.2006.08.001.

DOI:10.1016/j.cger.2006.08.001
PMID:17126752
Abstract

Heart failure (HF) represents the quintessential disorder of cardio-vascular aging, reflecting the convergence of age-related changes in the cardiovascular system and other organ systems and the increasing prevalence of cardiovascular diseases at older age. The prevalence and incidence of HF increase progressively with advancing age, and HF imposes an enormous burden on society in mortality,morbidity, and associated health care costs. Despite major advances in treatment of HF over the last 25 years, the prognosis re-mains poor, with median survival rates of less than 5 years in older adults. As the population ages, it is anticipated that the number of older people with HF will increase dramatically over the next several decades.

摘要

心力衰竭(HF)是心血管衰老的典型病症,反映了心血管系统和其他器官系统中与年龄相关的变化的汇聚,以及老年人心血管疾病患病率的不断上升。HF的患病率和发病率随着年龄的增长而逐渐增加,并且HF在死亡率、发病率和相关医疗保健成本方面给社会带来了巨大负担。尽管在过去25年中HF的治疗取得了重大进展,但预后仍然很差,老年人的中位生存率不到5年。随着人口老龄化,预计在未来几十年中,老年HF患者的数量将急剧增加。

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