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含银敷料及证据需求

Silver-containing dressings and the need for evidence.

作者信息

Hermans Michel H

机构信息

Hermans Consulting, Inc., Newton, PA, USA.

出版信息

Am J Nurs. 2006 Dec;106(12):60-8; quiz 68-9. doi: 10.1097/00000446-200612000-00025.

DOI:10.1097/00000446-200612000-00025
PMID:17133010
Abstract

The field of wound care has been inundated with "active" dressings--those that deliver biologically active substances to the wound site--and much attention has been given to those containing silver. Silver is a broad-spectrum agent: it is bactericidal to a large number of Gram-positive and Gram-negative microorganisms, many aerobes and anaerobes, and several antibiotic-resistant strains. More than 10 dressings containing pure silver are currently available; all claim to enhance wound healing through the antimicrobial activity of silver. But research findings on silver's antimicrobial efficacy are often inconclusive or contradictory. How, therefore, can clinicians decide which dressing is most appropriate for each patient? A grading system for reviewing the literature is presented.

摘要

伤口护理领域充斥着“活性”敷料——即那些能将生物活性物质输送到伤口部位的敷料——含银敷料备受关注。银是一种广谱抗菌剂:它对大量革兰氏阳性菌和革兰氏阴性菌、许多需氧菌和厌氧菌以及几种耐抗生素菌株具有杀菌作用。目前有10多种含纯银的敷料可供使用;所有这些敷料都声称可通过银的抗菌活性促进伤口愈合。但关于银的抗菌功效的研究结果往往没有定论或相互矛盾。那么,临床医生如何决定哪种敷料最适合每位患者呢?本文提出了一种用于文献综述的分级系统。

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Silver-containing dressings and the need for evidence.含银敷料及证据需求
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