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变应性支气管肺曲霉病:美国视角

Allergic bronchopulmonary aspergillosis: a US perspective.

作者信息

Virnig Christine, Bush Robert K

机构信息

William S. Middleton VA Hospital, Madison, Wisconsin 53705, USA.

出版信息

Curr Opin Pulm Med. 2007 Jan;13(1):67-71. doi: 10.1097/MCP.0b013e328010c812.

Abstract

PURPOSE OF REVIEW

The present article is an update of allergic bronchopulmonary aspergillosis. Although a rare condition, allergic bronchopulmonary aspergillosis does affect a number of patients with asthma and cystic fibrosis. Prompt recognition and treatment of the disease is critical to improving patient outcomes.

RECENT FINDINGS

There is currently much active research being performed in the area of allergic bronchopulmonary aspergillosis. Fascinating insights are being made into the pathophysiology and genetics of the disease. Additionally, research is ongoing on the use of recombinant Aspergillus allergens as an aid to the diagnosis of allergic bronchopulmonary aspergillosis.

SUMMARY

These new insights into the genetics and pathophysiology of allergic bronchopulmonary aspergillosis and the development of these new diagnostic techniques could ultimately lead to improved patient treatment. These areas form an important basis for further research.

摘要

综述目的

本文是关于变应性支气管肺曲霉病的最新进展。尽管变应性支气管肺曲霉病是一种罕见疾病,但它确实会影响许多哮喘和囊性纤维化患者。及时识别和治疗该疾病对于改善患者预后至关重要。

最新发现

目前在变应性支气管肺曲霉病领域有许多积极的研究正在进行。对该疾病的病理生理学和遗传学有了引人入胜的见解。此外,关于使用重组曲霉变应原辅助诊断变应性支气管肺曲霉病的研究也在进行中。

总结

这些对变应性支气管肺曲霉病遗传学和病理生理学的新见解以及这些新诊断技术的发展最终可能导致患者治疗的改善。这些领域构成了进一步研究的重要基础。

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