Yen Cheng-Fang, Kuo Chun-Ya, Tsai Pei-Tzu, Ko Chih-Hung, Yen Ju-Yu, Chen Tzu-Ting
Department of Psychiatry, College of Medicine, Kaohsiung Medical University, Kaohsiung, Taiwan.
Depress Anxiety. 2007;24(8):563-70. doi: 10.1002/da.20239.
Care of patients with panic disorder has raised quality-of-life (QOL) issues. The purpose of this study was to identify the level of QOL in patients with panic disorder and to examine the relationships between QOL and adverse effects of medication, social support, course of illness, psychopathology, and demographic characteristics. We recruited 57 patients with panic disorder from outpatient psychiatric clinics. We measured their QOL levels with the Short Form of the World Health Organization Questionnaire on Quality of Life-Taiwan Version (the WHOQOL-BREF Taiwan version) and examined the correlates of QOL. The analysis revealed that multiple factors were associated with poor QOL in patients with panic disorder, including severe adverse effects of medication for panic disorder, perceived low social support, severe current panic symptoms, total Beck Depression Inventory-II (BDI-II) score>/=17, young age, being unmarried, and early onset of panic disorder. The QOL of patients with panic disorder was correlated to multiple factors that were specific to individual subjects and influenced by interactions with treatment and the social environment. The results provide screening factors so that clinicians can intervene to improve QOL for their patients with panic disorder.
惊恐障碍患者的护理引发了生活质量（QOL）问题。本研究的目的是确定惊恐障碍患者的生活质量水平，并探讨生活质量与药物不良反应、社会支持、病程、精神病理学及人口统计学特征之间的关系。我们从门诊精神科诊所招募了57名惊恐障碍患者。我们使用世界卫生组织生活质量问卷简表-台湾版（WHOQOL-BREF台湾版）测量他们的生活质量水平，并研究生活质量的相关因素。分析显示，惊恐障碍患者生活质量差与多种因素相关，包括惊恐障碍药物的严重不良反应、感知到的低社会支持、当前严重的惊恐症状、贝克抑郁量表第二版（BDI-II）总分≥17、年轻、未婚以及惊恐障碍的早发。惊恐障碍患者的生活质量与多个特定于个体受试者的因素相关，并受到与治疗和社会环境相互作用的影响。研究结果提供了筛查因素，以便临床医生能够进行干预，改善其惊恐障碍患者的生活质量。
