Freisburger C, Goldmann K
Klinik für Anästhesie und Intensivtherapie, Universitätsklinikum Giessen-Marburg, Standort Marburg, Baldingerstrasse 1, 35033 Marburg.
Anaesthesist. 2006 Dec;55(12):1255-8. doi: 10.1007/s00101-006-1115-3.
The ProSeal laryngeal mask airway (PLMA) has been studied in numerous investigations and the airway leak pressure (P(leak)) is often used as a primary end-point, particularly in comparative studies with other supraglottic airway devices. The PLMA offers the opportunity to place a gastric tube through the drain-tube and P(leak) measurement can take place both with and without a gastric tube. With this study we tested the hypothesis that the use of a gastric tube influences the P(leak).
The P(leak) of the PLMA was studied in 98 patients under total intravenous anaesthesia with propofol (0.1-0.15 mgkgBW-1min-1) and remifentanil (0.1-0.3 microgkgBW-1min-1) before and after placement of a gastric tube through the drain-tube of the PLMA.
There was no significant difference between the mean baseline P(leak) without a gastric tube in place (25+/-6.3 cm H(2)O) and the mean P(leak) after placement of a gastric tube (25+/-6.7 cm H2O; p=0.6).
Placement of a gastric tube through the drain-tube of the PLMA does not influence the P(leak). Providing the same method of measurement has been used, P(leak) values from different studies obtained with or without a gastric tube in place are comparable.
在众多研究中对食管引流型喉罩气道（PLMA）进行了研究，气道泄漏压力（P(leak)）常被用作主要终点指标，尤其是在与其他声门上气道装置的对比研究中。PLMA提供了通过引流管插入胃管的机会，并且无论有无胃管都可以进行P(leak)测量。在本研究中，我们检验了使用胃管会影响P(leak)这一假设。
在98例接受丙泊酚（0.1 - 0.15 mgkgBW-1min-1）和瑞芬太尼（0.1 - 0.3 μgkgBW-1min-1）全静脉麻醉的患者中，通过PLMA的引流管插入胃管前后，研究PLMA的P(leak)。
未放置胃管时的平均基线P(leak)（25±6.3 cm H₂O）与放置胃管后的平均P(leak)（25±6.7 cm H₂O；p = 0.6）之间无显著差异。
通过PLMA的引流管插入胃管不会影响P(leak)。如果采用相同的测量方法，无论有无胃管，不同研究获得的P(leak)值都具有可比性。
