猿猴病毒肿瘤抗原：一种病毒特异性且预先存在的细胞蛋白。
Simian virus tumor antigen: a virus-specific and preexisting cell protein.
作者信息
Flügel R M, Fischer H
出版信息
J Natl Cancer Inst. 1975 Oct;55(4):899-901. doi: 10.1093/jnci/55.4.899.
PMID:171428
Abstract
The tumor (T) antigen of simian virus 40 (SV40)-transformed SV3T3 cells was immune precipitated with T antiserum obtained from hamsters bearing SV40-induced tumors and with rabbit antiserum to hamster cells. The resulting antigen-double antibody complexes were analyzed by sodium dodecyl sulfate polyacrylamide gel electrophoresis. Host components of SV40 T antigen with molecular weights of 70,000 and 30,000 were detected.
摘要
用从携带SV40诱导肿瘤的仓鼠获得的T抗血清以及兔抗仓鼠细胞血清对猿猴病毒40（SV40）转化的SV3T3细胞的肿瘤（T）抗原进行免疫沉淀。通过十二烷基硫酸钠聚丙烯酰胺凝胶电泳分析所得的抗原-双抗体复合物。检测到分子量为70,000和30,000的SV40 T抗原的宿主成分。
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