鼠伤寒沙门氏菌一个突变体中DNA合成的改变，该突变体使噬菌体P22倾向于溶原状态。
Altered DNA synthesis in a mutant of Salmonella typhimurium that channels bacteriophage P22 toward lysogeny.
作者信息
Steinberg B, Gough M
出版信息
J Virol. 1975 Nov;16(5):1154-60. doi: 10.1128/JVI.16.5.1154-1160.1975.
Abstract
Pox-1, a mutant of Salmonella typhimurium, strongly channels P22 toward lysogeny. Viral DNA synthesis in this slow-growing mutant is delayed to a greater extent than viral protein synthesis. The relative enhancement of c2 repressor synthesis results in much higher repressor/DNA synthesis ratios in Pox-1 than in wild-type cells. This probably accounts for the high frequency of lysogenization.
摘要
Pox-1是鼠伤寒沙门氏菌的一种突变体，它强烈地引导P22走向溶原状态。在这个生长缓慢的突变体中，病毒DNA合成比病毒蛋白质合成延迟的程度更大。c2阻遏物合成的相对增强导致Pox-1中阻遏物/DNA合成比率比野生型细胞中的高得多。这可能解释了溶原化的高频率。
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