噬菌体P22维持溶原性所必需的第二个位点。
Second locus of bacteriophage P22 necessary for the maintenance of lysogeny.
作者信息
Gough M
出版信息
J Virol. 1968 Oct;2(10):992-8. doi: 10.1128/JVI.2.10.992-998.1968.
Abstract
A temperature-sensitive allele of a locus of phage P22, known to be involved in establishment of lysogeny, has been isolated. This mutant, P22 ts mnt, forms stable lysogens at 30 C which are induced by heating to 43 C. This shows that this locus is involved in the maintenance of lysogeny. The ts mnt locus is about 18 recombination units away from the c region. The wild allele, mnt(+), is dominant over mnt and is responsible for a cytoplasmically diffusible product.
摘要
已分离出噬菌体P22一个基因座的温度敏感等位基因，已知该基因座参与溶原性的建立。这个突变体P22 ts mnt在30℃时形成稳定的溶原菌，加热到43℃会诱导其裂解。这表明该基因座参与溶原性的维持。ts mnt基因座距离c区域约18个重组单位。野生等位基因mnt(+)对mnt呈显性，负责一种可在细胞质中扩散的产物。
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