Stolzenburg Jens-Uwe, Rabenalt Robert, Do Minh, Tannapfel Andrea, Truss Michael C, Liatsikos Evangelos N
Department of Urology, University of Leipzig, Leipzig, Germany.
J Endourol. 2006 Nov;20(11):925-9. doi: 10.1089/end.2006.20.925.
To describe the various operative steps as well as the functional and oncologic results of nerve-sparing endoscopic extraperitoneal radical prostatectomy (nsEERP).
One hundred twenty preoperatively potent patients have been treated with bilateral nsEERPE in our department. The average age of the patients was 60.3 years (range 41-74 years), and the mean prostate weight was 48.6 g (range 24-117 g).
The mean operative time was 136 minutes (range 75-210 minutes). No conversions to open surgery were necessary. The mean catheterization time was 5.7 days (range 4-20 days). Lymphadenectomy was performed in 26 patients. The pathologic stages were pT2 in 78 and pT3 in 42 patients. Positive margins were detected in 7.7% (N = 6) and 19% (N = 8) of the patients with pT2 and pT3 disease, respectively. Erections sufficient for intercourse were reported in interviews with 58 patients (48.3%) during the 6-month follow-up period. Follow-up of at least 1 year is deemed necessary to draw more definite conclusions about erectile function. One week postoperatively, 32 patients (26.7%) required a maximum of 1 pad, 59 patients (49.2%) 2 or 3 pads, and 29 patients (24.2%) more than 3 pads per day because of incontinence, whereas 3 and 6 months after the procedure, 98 (82%) and 106 (88%) of the patients required a maximum of 1 pad, respectively.
Our results demonstrate that nsEERPE can be performed with equal efficacy and preliminary results similar to those of standard open radical prostatectomy as well as transperitoneal laparoscopic prostatectomy while completely avoiding intraperitoneal complications.
描述保留神经的内镜腹膜外根治性前列腺切除术(nsEERP)的各种手术步骤以及功能和肿瘤学结果。
我科对120例术前性功能正常的患者进行了双侧nsEERPE治疗。患者的平均年龄为60.3岁(范围41 - 74岁),平均前列腺重量为48.6 g(范围24 - 117 g)。
平均手术时间为136分钟(范围75 - 210分钟)。无需转为开放手术。平均导尿时间为5.7天(范围4 - 20天)。26例患者进行了淋巴结清扫。病理分期为pT2的有78例,pT3的有42例。pT2和pT3疾病患者中,分别有7.7%(N = 6)和19%(N = 8)检测到切缘阳性。在6个月的随访期内,通过访谈报告有58例患者(48.3%)勃起功能足以进行性交。为了对勃起功能得出更明确的结论,认为至少需要1年的随访。术后1周,32例患者(26.7%)每天最多需要1片尿垫,59例患者(49.2%)需要2或3片尿垫,29例患者(24.2%)因尿失禁每天需要超过3片尿垫;而在手术后3个月和6个月,分别有98例(82%)和106例(88%)患者每天最多需要1片尿垫。
我们的结果表明,nsEERPE可以以与标准开放根治性前列腺切除术以及经腹腹腔镜前列腺切除术相同的疗效和初步结果进行,同时完全避免腹腔内并发症。