Andrews David W, Bednarz Greg, Evans James J, Downes Beverly
Department of Neurological Surgery, Thomas Jefferson University Hospital, Philadelphia, PA 19107, USA.
Surg Neurol. 2006 Dec;66(6):559-64. doi: 10.1016/j.surneu.2006.08.002.
Stereotactic radiosurgery and fractionated stereotactic radiotherapy have become widespread techniques applied to the treatment of a variety of intracranial lesions. Rapid evolution of new technologies has now enabled clinicians to treat tumors outside the cranium and down the spinal axis. This review compares 3 commercially available systems in widespread use throughout the world.
Literature review and interviews with practitioners in the United States were performed to establish data for a comparative analysis of the Gamma Knife (Elekta, Sweden), Novalis (BrainLabs, Germany), and CyberKnife systems (Accuray, Sunnyvale, CA). Cost analyses were deliberately excluded because of the need for detailed cost-benefit analysis beyond the scope of the review.
An unbiased comparative analysis was not possible because of the lack of objective data from a standard metric for these systems. Despite this shortcoming, disparate features of each system were compared and contrasted.
A careful assessment of each system, including its operational features, capabilities, and yearly capacity must be weighed against the composition of the radiosurgery team, the case mix of the practice, and the objectives of the clinical unit to yield the best fit.
立体定向放射外科和分次立体定向放射治疗已成为广泛应用于治疗各种颅内病变的技术。新技术的迅速发展使临床医生能够治疗颅外和脊柱轴上的肿瘤。本综述比较了全球广泛使用的3种商用系统。
进行文献综述并采访美国的从业者,以建立数据,对伽玛刀(瑞典Elekta公司)、诺力刀(德国BrainLabs公司)和射波刀系统(加利福尼亚州森尼韦尔市Accuray公司)进行比较分析。由于需要超出综述范围的详细成本效益分析,故特意排除成本分析。
由于缺乏来自这些系统标准指标的客观数据,无法进行无偏倚的比较分析。尽管存在这一缺点,但仍对每个系统的不同特征进行了比较和对比。
必须根据放射外科团队的组成、业务的病例组合以及临床科室的目标,仔细评估每个系统,包括其操作特征、能力和年治疗量,以实现最佳匹配。