Dimitriadis Alexis, Palmer Antony L, Thomas Russell A S, Nisbet Andrew, Clark Catharine H
1 Faculty of Engineering and Physical Sciences, University of Surrey, Guildford, UK.
2 Department of Medical Physics, Royal Surrey County Hospital NHS Foundation Trust, Guildford, UK.
Br J Radiol. 2017 Jun;90(1074):20170053. doi: 10.1259/bjr.20170053. Epub 2017 May 25.
To adapt and validate an anthropomorphic head phantom for use in a cranial radiosurgery audit.
Two bespoke inserts were produced for the phantom: one for providing the target and organ at risk for delineation and the other for performing dose measurements. The inserts were tested to assess their positional accuracy. A basic treatment plan dose verification with an ionization chamber was performed to establish a baseline accuracy for the phantom and beam model. The phantom and inserts were then used to perform dose verification measurements of a radiosurgery plan. The dose was measured with alanine pellets, EBT extended dose film and a plastic scintillation detector (PSD).
Both inserts showed reproducible positioning (±0.5 mm) and good positional agreement between them (±0.6 mm). The basic treatment plan measurements showed agreement to the treatment planning system (TPS) within 0.5%. Repeated film measurements showed consistent gamma passing rates with good agreement to the TPS. For 2%-2 mm global gamma, the mean passing rate was 96.7% and the variation in passing rates did not exceed 2.1%. The alanine pellets and PSD showed good agreement with the TPS (-0.1% and 0.3% dose difference in the target) and good agreement with each other (within 1%).
The adaptations to the phantom showed acceptable accuracies. The presence of alanine and PSD do not affect film measurements significantly, enabling simultaneous measurements by all three detectors. Advances in knowledge: A novel method for thorough end-to-end test of radiosurgery, with capability to incorporate all steps of the clinical pathway in a time-efficient and reproducible manner, suitable for a national audit.
适配并验证一种用于颅脑放射外科审计的拟人化头部体模。
为该体模制作了两个定制插入件:一个用于提供用于勾画靶区和危及器官的结构,另一个用于进行剂量测量。对插入件进行测试以评估其位置准确性。使用电离室进行基本治疗计划剂量验证,以确定体模和射束模型的基线准确性。然后使用体模和插入件对放射外科计划进行剂量验证测量。使用丙氨酸颗粒、EBT扩展剂量胶片和塑料闪烁探测器(PSD)测量剂量。
两个插入件均显示出可重复的定位(±0.5毫米),且它们之间的位置一致性良好(±0.6毫米)。基本治疗计划测量结果与治疗计划系统(TPS)的一致性在0.5%以内。重复的胶片测量显示伽马通过率一致,与TPS的一致性良好。对于2%-2毫米全局伽马,平均通过率为96.7%,通过率的变化不超过2.1%。丙氨酸颗粒和PSD与TPS显示出良好的一致性(靶区剂量差异为-0.1%和0.3%),且它们之间的一致性良好(在1%以内)。
对体模的适配显示出可接受的准确性。丙氨酸和PSD的存在对胶片测量没有显著影响,使得所有三种探测器能够同时进行测量。知识进展:一种用于放射外科全面端到端测试的新方法,能够以高效且可重复的方式纳入临床路径的所有步骤,适用于全国性审计。