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本文引用的文献

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2
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3
Evaluation of Gafchromic EBT-XD film, with comparison to EBT3 film, and application in high dose radiotherapy verification.Gafchromic EBT-XD 胶片的评估,与 EBT3 胶片的比较及其在高剂量放射治疗验证中的应用。
Phys Med Biol. 2015 Nov 21;60(22):8741-52. doi: 10.1088/0031-9155/60/22/8741. Epub 2015 Oct 29.
4
Radiotherapy dosimetry audit: three decades of improving standards and accuracy in UK clinical practice and trials.放射治疗剂量学审核:英国临床实践与试验中三十年不断提高的标准与准确性
Br J Radiol. 2015;88(1055):20150251. doi: 10.1259/bjr.20150251. Epub 2015 Sep 2.
5
Evaluation and mitigation of potential errors in radiochromic film dosimetry due to film curvature at scanning.评估与减轻扫描时因薄膜弯曲导致的放射变色薄膜剂量测定中潜在误差的影响。
J Appl Clin Med Phys. 2015 Mar 8;16(2):5141. doi: 10.1120/jacmp.v16i2.5141.
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A multicentre 'end to end' dosimetry audit for cervix HDR brachytherapy treatment.一项针对宫颈癌高剂量率近距离放射治疗的多中心“端到端”剂量测定审核。
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Development of a modified head and neck quality assurance phantom for use in stereotactic radiosurgery trials.用于立体定向放射外科试验的改良头颈部质量保证体模的研制。
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Accuracy and sources of error of out-of field dose calculations by a commercial treatment planning system for intensity-modulated radiation therapy treatments.商业调强放射治疗计划系统计算野外剂量的准确性和误差源。
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用于颅部放射外科剂量测定端到端审核的商用头部体模的适配与验证。

Adaptation and validation of a commercial head phantom for cranial radiosurgery dosimetry end-to-end audit.

作者信息

Dimitriadis Alexis, Palmer Antony L, Thomas Russell A S, Nisbet Andrew, Clark Catharine H

机构信息

1 Faculty of Engineering and Physical Sciences, University of Surrey, Guildford, UK.

2 Department of Medical Physics, Royal Surrey County Hospital NHS Foundation Trust, Guildford, UK.

出版信息

Br J Radiol. 2017 Jun;90(1074):20170053. doi: 10.1259/bjr.20170053. Epub 2017 May 25.

DOI:10.1259/bjr.20170053
PMID:28452563
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC5602186/
Abstract

OBJECTIVE

To adapt and validate an anthropomorphic head phantom for use in a cranial radiosurgery audit.

METHODS

Two bespoke inserts were produced for the phantom: one for providing the target and organ at risk for delineation and the other for performing dose measurements. The inserts were tested to assess their positional accuracy. A basic treatment plan dose verification with an ionization chamber was performed to establish a baseline accuracy for the phantom and beam model. The phantom and inserts were then used to perform dose verification measurements of a radiosurgery plan. The dose was measured with alanine pellets, EBT extended dose film and a plastic scintillation detector (PSD).

RESULTS

Both inserts showed reproducible positioning (±0.5 mm) and good positional agreement between them (±0.6 mm). The basic treatment plan measurements showed agreement to the treatment planning system (TPS) within 0.5%. Repeated film measurements showed consistent gamma passing rates with good agreement to the TPS. For 2%-2 mm global gamma, the mean passing rate was 96.7% and the variation in passing rates did not exceed 2.1%. The alanine pellets and PSD showed good agreement with the TPS (-0.1% and 0.3% dose difference in the target) and good agreement with each other (within 1%).

CONCLUSION

The adaptations to the phantom showed acceptable accuracies. The presence of alanine and PSD do not affect film measurements significantly, enabling simultaneous measurements by all three detectors. Advances in knowledge: A novel method for thorough end-to-end test of radiosurgery, with capability to incorporate all steps of the clinical pathway in a time-efficient and reproducible manner, suitable for a national audit.

摘要

目的

适配并验证一种用于颅脑放射外科审计的拟人化头部体模。

方法

为该体模制作了两个定制插入件:一个用于提供用于勾画靶区和危及器官的结构,另一个用于进行剂量测量。对插入件进行测试以评估其位置准确性。使用电离室进行基本治疗计划剂量验证,以确定体模和射束模型的基线准确性。然后使用体模和插入件对放射外科计划进行剂量验证测量。使用丙氨酸颗粒、EBT扩展剂量胶片和塑料闪烁探测器(PSD)测量剂量。

结果

两个插入件均显示出可重复的定位(±0.5毫米),且它们之间的位置一致性良好(±0.6毫米)。基本治疗计划测量结果与治疗计划系统(TPS)的一致性在0.5%以内。重复的胶片测量显示伽马通过率一致,与TPS的一致性良好。对于2%-2毫米全局伽马,平均通过率为96.7%,通过率的变化不超过2.1%。丙氨酸颗粒和PSD与TPS显示出良好的一致性(靶区剂量差异为-0.1%和0.3%),且它们之间的一致性良好(在1%以内)。

结论

对体模的适配显示出可接受的准确性。丙氨酸和PSD的存在对胶片测量没有显著影响,使得所有三种探测器能够同时进行测量。知识进展:一种用于放射外科全面端到端测试的新方法,能够以高效且可重复的方式纳入临床路径的所有步骤,适用于全国性审计。