Marenduzzo Davide, Finan Kieran, Cook Peter R
School of Physics, University of Edinburgh, Edinburgh, EH9 3JZ, Scotland, UK.
J Cell Biol. 2006 Dec 4;175(5):681-6. doi: 10.1083/jcb.200609066.
Cellular structures are shaped by hydrogen and ionic bonds, plus van der Waals and hydrophobic forces. In cells crowded with macromolecules, a little-known and distinct force-the "depletion attraction"-also acts. We review evidence that this force assists in the assembly of a wide range of cellular structures, ranging from the cytoskeleton to chromatin loops and whole chromosomes.
细胞结构由氢键、离子键以及范德华力和疏水作用力塑造而成。在充满大分子的细胞中，一种鲜为人知且独特的力——“排空吸引作用”——也在发挥作用。我们回顾了相关证据，表明这种力有助于多种细胞结构的组装，从细胞骨架到染色质环乃至整条染色体。
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