Tiede Jeffrey M, Ghazi Salim M, Lamer Tim J, Obray Jon B
Department of Pain Management, Mayo Clinic College of Medicine, Jacksonville, Florida 32224, USA.
Pain Pract. 2006 Sep;6(3):197-202. doi: 10.1111/j.1533-2500.2006.00085.x.
Patients will commonly seek medical attention for refractory abdominal pain. The many causes of abdominal pain include pathologies of the gastrointestinal, genitourinary, musculoskeletal, and nervous systems. Unfortunately, a large number of patients will develop chronic abdominal pain that is recalcitrant to definitive therapies and nonspecific treatments such as cognitive-behavioral, physical, and pharmacologic therapies. Although spinal cord stimulation is classically used for neuropathic and ischemic conditions, a growing number of reports describe its efficacy in visceral disease. We describe our experience with spinal cord stimulation in two patients with refractory abdominal pain. Although the exact etiology in these complex patients is not defined, it is theorized that visceral hypersensitivity is at least one component. Finally, we will summarize the applicable literature in order to explain a possible mechanism of analgesia in visceral disease.
患者通常会因顽固性腹痛而寻求医疗帮助。腹痛的原因众多,包括胃肠道、泌尿生殖系统、肌肉骨骼系统和神经系统的病变。不幸的是,大量患者会出现慢性腹痛,这种腹痛对诸如认知行为、物理和药物治疗等确定性疗法以及非特异性治疗均无反应。尽管脊髓刺激传统上用于治疗神经病变和缺血性疾病,但越来越多的报告描述了其在内脏疾病中的疗效。我们描述了我们对两名顽固性腹痛患者进行脊髓刺激的经验。尽管这些复杂患者的确切病因尚未明确,但据推测内脏超敏反应至少是其中一个因素。最后,我们将总结相关文献,以解释内脏疾病中可能的镇痛机制。