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新生儿全胃肠外营养

Total parenteral nutrition in neonates.

作者信息

Chaudhari Sudha, Kadam Sandeep

机构信息

Division of Neonatology, Department of Pediatrics, KEM Hospital, Pune 411 011, Maharashtra, India.

出版信息

Indian Pediatr. 2006 Nov;43(11):953-64.

Abstract

Parenteral Nutrition (PN) allows us to meet a neonates requirement for growth and development when their size or condition precludes enteral feeding. Although feeding through the gastrointestinal tract is the preferred route for nutritional management, there are specific conditions where PN as an adjunctive or sole therapy is necessary. In very low birth weight premature infants, due to the immaturity of the gastrointestinal systems, enteral feeding cannot be established in the first few days of life. In critically ill neonates, neonates with protracted diarrhea and neonates who have had major GI surgery, PN can successfully meet the nutritional demands. Parenteral Nutrition solutions, although still evolving, have improved considerably since the early days and complications are now less common when amino acids and lipids are given in a dose of 1-3 g / kg / day. Meticulous attention to asepsis, good nursing care and close biochemical monitoring are absolutely essential for successful PN therapy.

摘要

当新生儿的体型或状况不适合经肠道喂养时,肠外营养(PN)使我们能够满足其生长发育的需求。尽管经胃肠道喂养是营养管理的首选途径,但在某些特定情况下,PN作为辅助或唯一疗法是必要的。对于极低出生体重的早产儿,由于胃肠系统不成熟,在出生后的头几天无法建立经肠道喂养。在危重新生儿、患有迁延性腹泻的新生儿以及接受过重大胃肠道手术的新生儿中,PN能够成功满足营养需求。肠外营养溶液虽然仍在不断发展,但自早期以来已有了很大改进,如今当氨基酸和脂质的给药剂量为1 - 3克/千克/天时,并发症已不那么常见。对无菌操作的精心关注、良好的护理以及密切的生化监测对于成功的PN治疗绝对至关重要。

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