Suppr超能文献

双侧唇腭裂患者面部内侧部分的发育障碍,特别考虑鼻子的情况

[Developmental disturbances of medial part of face of patients with bilateral cleft lip and palate with special consideration of a nose].

作者信息

Nieczuj-Urbańska Joanna, Sitek Aneta, Kruk-Jeromin Julia, Antoszewski Bogusław

机构信息

Katedra Antropologii Uniwersytetu Lódzkiego.

出版信息

Otolaryngol Pol. 2006;60(4):537-42.

Abstract

UNLABELLED

Cleft is a developmental malformation, which is defined as a partial or complete lack of anatomic tissues continuity in typical areas of disorders in embryological face development. The reasons for cleft formation are not completely recognised but many hypotheses indicate both environmental and genetic factors as possible sources. The list of the cleft types is the following: cleft lip, cleft lip and alveolus, isolated cleft palate, cleft lip, alveolus and palate, and combined clefts. The malformation may occur unilateral or bilateral. According to World Health Organization cleft lip and palate is classified in the first ten of the most common developmental disorders, however the bilateral form of pathology is the least popular one.

MATERIAL AND METHODS

The aim of the study is the anthropometric measurement of a nose of children and adolescents with bilateral cleft lip, alveolus and palate in comparison with data gathered as a result of healthy people measurements. The research was conducted on 26 patients with the malformation: 12 girls and 14 boys at the age range between 7 and 18. The measurements were taken with the use of small bow and slide compasses. For the purpose of the statistical analysis we used formula for standardisation. Both, the arithmetic average and the standard deviation were estimated on the basis of research done on 30 healthy people of same sex and at proper age. Intersexual comparison of these values with the use of t-Student test was done. In order to distinguish homologues features in respect to the comparative group, one-way ANOVA and test post hoc (Duncan) were used.

RESULTS

Malformation was mainly reflected in increased width the base of the nose (sbal-sbal), width of nose (al-al) and its small prominence (sn-prn). Increase in head height values together with underdevelopment in sagittal plane was also observable. The increase of upper face height (n-sto) was recognized as stronger in case of females than males with the same malformation. The middle part of face was characterized by increase of height measurements together with sagittal plane underdevelopment.

CONCLUSIONS

It was stated that the patients with bilateral cleft lip, alveolus and palate tended to have flat and wide nose.

摘要

未标注

腭裂是一种发育畸形,其定义为胚胎面部发育紊乱典型区域的解剖组织连续性部分或完全缺失。腭裂形成的原因尚未完全明确,但许多假说表明环境和遗传因素都可能是其成因。腭裂类型如下:唇裂、唇裂合并牙槽突裂、孤立性腭裂、唇裂合并牙槽突裂及腭裂、复合性腭裂。这种畸形可单侧或双侧发生。根据世界卫生组织的分类,唇腭裂位列最常见的十大发育障碍之中,然而双侧病理形式最为少见。

材料与方法

本研究旨在对双侧唇裂合并牙槽突裂及腭裂的儿童和青少年的鼻部进行人体测量,并与健康人群测量所得数据进行比较。研究对象为26例患有该畸形的患者,其中12名女孩和14名男孩,年龄在7至18岁之间。测量使用小型弓形和滑动圆规进行。为进行统计分析,我们使用了标准化公式。基于对30名同性别且年龄合适的健康人群的研究,估算了算术平均值和标准差。使用t检验对这些值进行两性间比较。为了区分与对照组相对应的特征值,采用了单向方差分析和事后检验(邓肯检验)。

结果

畸形主要表现为鼻基底宽度(sbal-sbal)、鼻宽(al-al)及其微小突出度(sn-prn)增加。还可观察到头高值增加以及矢状面发育不全。对于患有相同畸形的女性,其上脸高度(n-sto)的增加比男性更为明显。面部中部的特征是高度测量值增加以及矢状面发育不全。

结论

研究表明,双侧唇裂合并牙槽突裂及腭裂的患者往往有扁平且宽阔的鼻子。

文献检索

告别复杂PubMed语法,用中文像聊天一样搜索,搜遍4000万医学文献。AI智能推荐,让科研检索更轻松。

立即免费搜索

文件翻译

保留排版,准确专业,支持PDF/Word/PPT等文件格式,支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述,25分钟生成高质量综述,智能提取关键信息,辅助科研写作。

立即免费体验