Hopwood P, Thatcher N
Department of Medical Oncology, Christie Hospital and Holt Radium Institute, Manchester, UK.
Oncology (Williston Park). 1991 May;5(5):159-166; discussion 166, 169, 173.
Quality of life in patients with inoperable lung cancer receiving palliative treatment has become an important issue. As in other types of cancer, lack of standardization of quality of life data makes comparison between trials difficult, sometimes even impossible. Much effort is being given to the development of suitable instruments to measure quality of life and strategies to incorporate these measurements into clinical trials. The authors review studies in palliative lung cancer treatment where two crucial questions are being addressed: Do patients improve in performance status and symptom relief and does treatment toxicity outweigh disease palliation?
接受姑息治疗的无法手术的肺癌患者的生活质量已成为一个重要问题。与其他类型的癌症一样，生活质量数据缺乏标准化使得试验之间的比较变得困难，有时甚至不可能。目前正在大力开发合适的工具来测量生活质量，并制定将这些测量纳入临床试验的策略。作者回顾了姑息性肺癌治疗的研究，其中涉及两个关键问题：患者的功能状态和症状缓解是否有所改善，治疗毒性是否超过疾病缓解？
