Spangenberg H C, Mohr L, Blum H E
Abteilung Innere Medizin II, Medizinische Klinik der Universität, 79106, Hugstetter Strasse 55, Freiburg, Germany.
Internist (Berl). 2007 Jan;48(1):40-5. doi: 10.1007/s00108-006-1771-z.
Malignant liver tumors are either originating from the liver, such as the primary liver tumors hepatocellular carcinoma and the cholangiocellular carcinoma, or metastases from extrahepatic malignancies. Apart from surgical procedures (resection, liver transplantation) percutaneous local-ablative (ethanol injection, radiofrequency thermal ablation as well as radiation therapy) and transarterial interventions are non-surgical therapeutic options. While these regional therapies have been shown in randomised controlled studies to be effective for hepatocellular carcinoma, their therapeutic efficacy in cholangiocellular carcinoma and liver metastases has not been shown. In the following we will summarize the regional therapeutic options in primary and secondary liver tumors.
恶性肝肿瘤要么起源于肝脏，如原发性肝肿瘤肝细胞癌和胆管细胞癌，要么是肝外恶性肿瘤的转移灶。除了外科手术（切除、肝移植）外，经皮局部消融（乙醇注射、射频热消融以及放射治疗）和经动脉介入是无创治疗选择。虽然这些局部治疗在随机对照研究中已显示对肝细胞癌有效，但其在胆管细胞癌和肝转移瘤中的治疗效果尚未得到证实。以下我们将总结原发性和继发性肝肿瘤的局部治疗选择。
