脊椎动物中的晶状体诱导：信号事件保守主题的变体
Lens induction in vertebrates: variations on a conserved theme of signaling events.
作者信息
Donner Amy L, Lachke Salil A, Maas Richard L
机构信息
Division of Genetics, Department of Medicine, Brigham and Women's Hospital, Harvard Medical School, Boston, MA 02115, USA.
出版信息
Semin Cell Dev Biol. 2006 Dec;17(6):676-85. doi: 10.1016/j.semcdb.2006.10.005. Epub 2006 Oct 27.
This review provides an overview of our current understanding of signaling mechanisms involved in lens induction, which are presented in context of the major stages of lens induction (competence, bias, inhibition and specification). Although the process of lens induction is generally well conserved, we highlight aspects of induction that vary among species. Finally, this review identifies future challenges in forming an integrated network of signaling pathways involved in lens induction.
本综述概述了我们目前对晶状体诱导过程中涉及的信号传导机制的理解，这些机制是在晶状体诱导的主要阶段（感受态、偏向、抑制和特化）的背景下呈现的。尽管晶状体诱导过程总体上保守性良好，但我们强调了不同物种间诱导过程存在差异的方面。最后，本综述确定了在构建参与晶状体诱导的信号通路综合网络方面未来面临的挑战。
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