Department of Cell and Developmental Biology, University of Illinois, Urbana, IL.
Department of Biology, Illinois College, Jacksonville, IL.
Mol Biol Evol. 2018 Jul 1;35(7):1563-1575. doi: 10.1093/molbev/msy045.
In this review, we compare and contrast the three different forms of vertebrate lens regeneration: Wolffian lens regeneration, cornea-lens regeneration, and lens regeneration from lens epithelial cells. An examination of the diverse cellular origins of these lenses, their unique phylogenetic distribution, and the underlying molecular mechanisms, suggests that these different forms of lens regeneration evolved independently and utilize neither conserved nor convergent mechanisms to regulate these processes.
在这篇综述中,我们比较和对比了三种不同形式的脊椎动物晶状体再生:沃尔夫氏晶状体再生、角膜-晶状体再生和晶状体上皮细胞的晶状体再生。对这些晶状体的不同细胞起源、独特的系统发育分布以及潜在的分子机制的研究表明,这些不同形式的晶状体再生是独立进化的,既没有利用保守的机制,也没有利用趋同的机制来调节这些过程。