Russo V, Gostoli V, Lovato L, Montalti M, Marzocchi A, Gavelli G, Branzi A, Di Bartolomeo R, Fattori R
Cardiovascular Department, Cardiovascular Radiology Unit, University Hospital S. Orsola, Padiglione 21, Via Massarenti 9, 40138 Bologna, Italy.
Heart. 2007 Dec;93(12):1591-8. doi: 10.1136/hrt.2006.105023. Epub 2006 Dec 12.
Myocardial scintigraphy and/or conventional angiography (CA) are often performed before cardiac surgery in an attempt to identify unsuspected coronary artery disease which might result in significant cardiac morbidity and mortality. Multidetector CT coronary angiography (MDCTCA) has a recognised high negative predictive value and may provide a non-invasive alternative in this subset of patients. The aim of this study was to evaluate the clinical value of MDCTCA as a preoperative screening test in candidates for non-coronary cardiac surgery.
132 patients underwent MDCTCA (Somatom Sensation 16 Cardiac, Siemens) in the assessment of the cardiac risk profile before surgery. Coronary arteries were screened for > or = 50% stenosis. Patients without significant stenosis (Group 1) underwent surgery without any adjunctive screening tests while all patients with coronary lesions > or = 50% at MDCTCA (Group 2) underwent CA.
16 patients (12.1%) were excluded due to poor image quality. 72 patients without significant coronary stenosis at MDCTCA were submitted to surgery. 30 out of 36 patients with significant (> or = 50%) coronary stenosis at MDCTCA and CA underwent adjunctive bypass surgery or coronary angioplasty. In 8 patients, MDCTCA overestimated the severity of the coronary lesions (> 50% MDCTCA, < 50% CA). No severe cardiovascular perioperative events such as myocardial ischaemia, myocardial infarction or cardiac failure occurred in any patient in Group 1.
MDCTCA seems to be effective as a preoperative screening test prior to non-coronary cardiac surgery. In this era of cost containment and optimal care of patients, MDCTCA is able to provide coronary vessel and ventricular function evaluation and may become the method of choice for the assessment of a cardiovascular risk profile prior to major surgery.
心肌闪烁显像和/或传统血管造影术(CA)常在心脏手术前进行,旨在识别可能导致严重心脏发病和死亡的未被怀疑的冠状动脉疾病。多排CT冠状动脉造影(MDCTCA)具有公认的高阴性预测价值,可能为这部分患者提供一种非侵入性替代方法。本研究的目的是评估MDCTCA作为非冠状动脉心脏手术候选者术前筛查试验的临床价值。
132例患者在手术前接受MDCTCA(西门子Somatom Sensation 16心脏型)评估心脏风险状况。对冠状动脉进行筛查,以确定是否存在≥50%的狭窄。无明显狭窄的患者(第1组)在不进行任何辅助筛查试验的情况下接受手术,而所有在MDCTCA检查中冠状动脉病变≥50%的患者(第2组)接受CA检查。
16例患者(12.1%)因图像质量差被排除。72例在MDCTCA检查中无明显冠状动脉狭窄的患者接受了手术。在MDCTCA和CA检查中冠状动脉狭窄≥50%的36例患者中,30例接受了辅助搭桥手术或冠状动脉成形术。8例患者中,MDCTCA高估了冠状动脉病变的严重程度(MDCTCA显示>50%,CA显示<50%)。第1组患者中没有发生任何严重的心血管围手术期事件,如心肌缺血、心肌梗死或心力衰竭。
MDCTCA似乎作为非冠状动脉心脏手术前的术前筛查试验是有效的。在这个成本控制和患者最佳护理的时代,MDCTCA能够提供冠状动脉血管和心室功能评估,并可能成为大手术前评估心血管风险状况的首选方法。