Perry Tamara T, Wood Robert A, Matsui Elizabeth C, Curtin-Brosnan Jean, Rand Cynthia, Eggleston Peyton A
Department of Pediatrics, Division of Allergy and Immunology, University of Arkansas for Medical Sciences College of Medicine, Arkansas Children's Hospital Research Institute, Little Rock, Arkansas 72202, USA.
Ann Allergy Asthma Immunol. 2006 Nov;97(5):628-35. doi: 10.1016/S1081-1206(10)61092-7.
Room characteristics predicting indoor allergen exposure in suburban homes have not been clearly identified.
To examine relationships between room characteristics and concentrations of indoor allergens in homes of suburban asthmatic patients.
The homes of 339 asthmatic children ages 6 to 17 years were studied. Home inspections were conducted by a trained technician, and dust samples were analyzed for indoor allergen content. A high allergen concentration was defined as 8 microg (U)/g or more of fine dust.
Infrequent sheet washing and wall-to-wall carpet were risk factors for high bedroom dust mite concentrations. Infrequent sheet washing was also a risk factor for high Fel d 1 concentrations. Food remains in the bedroom was a risk factor for high bedroom Bla g 1 levels, and exposed food, leaks, and dirty pots were all risk factors for high kitchen Bla g 1 levels. The combination of lack of mattress or pillow encasements, infrequent sheet washing, and carpeting was associated with a 24-fold increase in odds of a high dust mite concentration (odds ratio [OR], 24.1; 95% confidence interval [CI], 3.2-181.4). Among non-cat owners, the combination of stuffed toys on the bed, lack of mattress or pillow encasements, and infrequent sheet washing was associated with a 49-fold increase in odds of a high Fel d 1 level (OR, 49.4; 95% CI, 2.8-887.3). The combination of leaks, exposed food, and dirty pots was associated with a high kitchen Bla g 1 concentration (OR, 10.6; 95% CI, 2.8-40.5).
Specific room characteristics predict high indoor allergen exposure among children with asthma, and a combination of these characteristics may further increase the risk of high allergen exposure.
尚未明确确定预测郊区家庭室内过敏原暴露的房间特征。
研究郊区哮喘患者家中房间特征与室内过敏原浓度之间的关系。
对339名6至17岁哮喘儿童的家庭进行了研究。由一名经过培训的技术人员进行家庭检查，并对灰尘样本进行室内过敏原含量分析。高过敏原浓度定义为细粉尘中8微克（单位）/克或更多。
不经常清洗床单和满铺地毯是卧室尘螨浓度高的危险因素。不经常清洗床单也是高猫过敏原1浓度的危险因素。卧室里有食物残渣是卧室里高黑曲霉1水平的危险因素，而暴露的食物、漏水和脏锅都是厨房高黑曲霉1水平的危险因素。缺少床垫或枕头套、不经常清洗床单和铺地毯的组合与高尘螨浓度的几率增加24倍相关（优势比[OR]，24.1；95%置信区间[CI]，3.2 - 181.4）。在非养猫家庭中，床上有填充玩具、缺少床垫或枕头套以及不经常清洗床单的组合与高猫过敏原1水平的几率增加49倍相关（OR，49.4；95% CI，2.8 - 887.3）。漏水、暴露的食物和脏锅的组合与厨房高黑曲霉1浓度相关（OR，10.6；95% CI，2.8 - 40.5）。
特定的房间特征可预测哮喘儿童的高室内过敏原暴露，这些特征的组合可能会进一步增加高过敏原暴露的风险。
