Chew G L, Burge H A, Dockery D W, Muilenberg M L, Weiss S T, Gold D R
Department of Environmental Health, Harvard School of Public Health, Boston, Massachusetts, USA.
Am J Respir Crit Care Med. 1998 May;157(5 Pt 1):1536-41. doi: 10.1164/ajrccm.157.5.9708011.
We examined associations between reported home characteristics and levels of indoor allergens in 499 homes of a birth cohort of children of allergic/asthmatic families from the Boston area. The risk of having dust mite allergen (Der f 1 or Der p 1) > or = 2 microg/g on the bedroom floor was highest in houses, but 16% of apartments had levels this high. Compared with that from smooth floors, dust from carpeted bedroom floors had 2.1 times the risk of dust mite allergen > or = 10 microg/g, but levels exceeded 2 microg/g in 32% of uncarpeted floors. The risk of dust mite allergen > or = 10 microg/g of dust from plastic-encased mattresses was 0.5 times that for cloth mattresses, but levels in 21% of plastic-encased mattresses were > or = 2 microg/g. In 93% of homes with and 3% of homes without cats, Fel d 1 was > or = 8 microg/g, but 34% of homes without cats had Fed d 1 > or = 1 microg/g. Cockroach allergen (Bla g 1 or Bla g 2) was > or = 2 U/g of kitchen dust in 26% of apartments and only 6% of houses, and it was detected in 48% of homes with no reported signs of cockroaches in the previous 12 mo. Home characteristics reporting is a relatively weak predictor of the absence of allergen, and exposure can occur even when no cats are present, beds are encased in plastic, no carpets are present, and no signs of cockroaches have been reported.
我们调查了波士顿地区过敏/哮喘家庭出生队列中499个家庭报告的家庭特征与室内过敏原水平之间的关联。卧室地板上尘螨过敏原(Der f 1或Der p 1)≥2微克/克的风险在房屋中最高,但16%的公寓也有如此高的水平。与光滑地板相比,铺有地毯的卧室地板灰尘中尘螨过敏原≥10微克/克的风险是其2.1倍,但在32%的未铺地毯的地板上,该水平也超过了2微克/克。塑料包裹床垫的灰尘中尘螨过敏原≥10微克/克的风险是布质床垫的0.5倍,但21%的塑料包裹床垫中该水平≥2微克/克。在有猫的家庭中93%以及无猫的家庭中3%,猫过敏原(Fel d 1)≥8微克/克,但34%无猫的家庭中猫过敏原(Fed d 1)≥1微克/克。蟑螂过敏原(Bla g 1或Bla g 2)在26%的公寓和仅6%的房屋的厨房灰尘中≥2单位/克,并且在前12个月内没有蟑螂迹象报告的家庭中,48%检测到了蟑螂过敏原。家庭特征报告对于不存在过敏原的预测相对较弱,即使没有猫、床用塑料包裹、没有地毯且没有蟑螂迹象报告,暴露仍可能发生。