Kanaan I, Jallu A, Alwatban J, Patay Z, Hessler R
Skull Base. 2001 Nov;11(4):287-95. doi: 10.1055/s-2001-18635.
Two patients with extra-axial cavernous hemangioma who presented with headache and oculovisual disturbances were investigated with computed tomography and magnetic resonance imaging. The lesions masqueraded as basal meningioma, but this diagnosis was not supported by magnetic resonance spectroscopy in one patient. Cerebral angiography with embolization was indicated in one patient, but embolization was not justified in the other. Both patients underwent a pterional craniotomy. The lesions were extradural and highly vascular, necessitating excessive transfusion in one patient in whom gross total resection was achieved, and precluding satisfactory removal in the other. There was no mortality. Transient ophthalmoplegia, the only complication in one patient, was due to surgical manipulation of the cavernous sinus; it resolved progressively over 3 months. Extra-axial skull base cavernous hemangiomas are distinct entities with clinical and radiological characteristics that differ from those of intraparenchymal cavernous malformations. They can mimic meningiomas or pituitary tumors. In some cases, magnetic resonance spectroscopy may narrow the differential diagnoses. Surgical resection remains the treatment of choice, facilitated by preoperative embolization to reduce intraoperative bleeding and by the application of the principles of skull base surgery. Fractionated radiotherapy is an alternative in partial or difficult resections and in high-risk and elderly patients.
两名患有轴外海绵状血管瘤的患者,表现为头痛和视觉障碍,接受了计算机断层扫描和磁共振成像检查。病变伪装成基底脑膜瘤,但其中一名患者的磁共振波谱分析不支持这一诊断。一名患者接受了脑血管造影及栓塞治疗,但另一名患者的栓塞治疗并不合理。两名患者均接受了翼点开颅手术。病变位于硬膜外且血管丰富,其中一名实现了肿瘤全切的患者术中需要大量输血,另一名患者则无法实现满意的切除。患者均无死亡。一名患者唯一的并发症是短暂性眼肌麻痹,系海绵窦手术操作所致,3个月内逐渐缓解。轴外颅底海绵状血管瘤是具有独特临床和影像学特征的实体,与脑实质内海绵状畸形不同。它们可模仿脑膜瘤或垂体瘤。在某些情况下,磁共振波谱分析可缩小鉴别诊断范围。手术切除仍是首选治疗方法,术前栓塞可减少术中出血,应用颅底手术原则有助于手术进行。对于部分切除或困难切除的病例以及高危和老年患者,分次放疗是一种替代治疗方法。