Vollenweider P, Hayoz D, Preisig M, Pécoud A, Warterworht D, Mooser V, Paccaud F, Waeber G
Service de médecine interne, CHUV 1011 Lausanne.
Rev Med Suisse. 2006 Nov 8;2(86):2528-30, 2532-3.
Cardiovascular diseases (CVD) remain the main cause of morbidity and mortality in our society. CoLaus is a population-based health examination survey started in 2003 in Lausanne in order to assess: 1. Prevalence of cardiovascular risk factors, 2. New genetic determinants of cardiovascular risk factors such as hypertension, 3. Association of mood disorders with incidence of cardiovascular events and 4. Trends in prevalence of cardiovascular risk factors. In order to do so, over 6000 subjects (ages 35-75 years) provided data on CVD risk factors. Herein we provide preliminary results of this study, in particular on classical risk factors such as hypertension, obesity and diabetes. Implications and perspectives of this population based-study for public health and genetic studies are also discussed.
心血管疾病(CVD)仍然是我们社会中发病和死亡的主要原因。CoLaus是一项基于人群的健康检查调查,于2003年在洛桑启动,目的是评估:1. 心血管危险因素的患病率;2. 心血管危险因素(如高血压)的新遗传决定因素;3. 情绪障碍与心血管事件发生率的关联;4. 心血管危险因素患病率的趋势。为了实现这一目标,6000多名受试者(年龄在35至75岁之间)提供了有关心血管疾病危险因素的数据。在此,我们提供这项研究的初步结果,特别是关于高血压、肥胖和糖尿病等经典危险因素的结果。还讨论了这项基于人群的研究对公共卫生和基因研究的意义及前景。