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颞骨巨细胞瘤:治疗策略

Giant-cell tumors of the temporal bone: management strategies.

作者信息

Isaacson Brandon, Berryhill Wayne, Arts H Alexander

机构信息

Department of Otolaryngology-Head and Neck Surgery, University of Texas Southwestern Medical Center, Dallas, Texas.

出版信息

Skull Base. 2009 Jul;19(4):291-301. doi: 10.1055/s-0028-1115324.

Abstract

OBJECTIVE

To discuss the current management options for giant-cell tumors (GCTs) involving the temporal bone and present two case reports and a review of the literature.

METHOD

In a tertiary-care academic medical center, two patients with GCTs of the temporal bone were evaluated and managed. The patients underwent gross total resection and curettage of GCTs involving the temporal bone. Afterward, both patients were evaluated for postoperative complications as well as for recurrence.

RESULTS

Two patients underwent operative excision using curettage. Clinical and radiographic studies demonstrated no evidence of recurrence with 3 years of follow-up in one patient and 10 years of follow-up in the second patient.

CONCLUSION

Based on these results, we concluded that gross total removal and curettage of GCTs in the temporal bone is a viable treatment option. This finding is contrary to previous studies.

摘要

目的

探讨累及颞骨的骨巨细胞瘤(GCTs)的当前治疗选择,并呈现两例病例报告及文献综述。

方法

在一家三级医疗学术医学中心,对两名患有颞骨GCTs的患者进行了评估和治疗。患者接受了累及颞骨的GCTs的全切除和刮除术。术后,对两名患者的术后并发症及复发情况进行了评估。

结果

两名患者均接受了刮除术切除。临床和影像学研究表明,一名患者随访3年,另一名患者随访10年,均无复发迹象。

结论

基于这些结果,我们得出结论,颞骨GCTs的全切除和刮除术是一种可行治疗选择。这一发现与先前研究相反。

相似文献

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Giant-cell tumors of the temporal bone: management strategies.颞骨巨细胞瘤:治疗策略
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本文引用的文献

1
Giant cell tumor of bone express p63.骨巨细胞瘤表达p63。
Mod Pathol. 2008 Apr;21(4):369-75. doi: 10.1038/modpathol.2008.29. Epub 2008 Feb 29.
7
Malignancy in giant cell tumor of bone.骨巨细胞瘤中的恶性肿瘤
Cancer. 2003 May 15;97(10):2520-9. doi: 10.1002/cncr.11359.
9
The nature of giant cell tumor of bone.骨巨细胞瘤的本质。
J Cancer Res Clin Oncol. 2001 Aug;127(8):467-74. doi: 10.1007/s004320100234.

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