皮肤科结缔组织病的最新进展。

Update on connective tissue diseases in dermatology.

作者信息

Costner Melissa I, Grau Renee H

机构信息

Department of Dermatology, University of Texas Southwestern Medical Center at Dallas, Dallas, TX 75390-9190, USA.

出版信息

Semin Cutan Med Surg. 2006 Dec;25(4):207-20. doi: 10.1016/j.sder.2006.08.004.

DOI:10.1016/j.sder.2006.08.004

PMID:17174841

Abstract

Recent advances in understanding the pathogenesis of autoimmune diseases, including lupus erythematosus, dermatomyositis, and scleroderma, have allowed for reorganization of the classification of these disorders. With these novel stratifications, early identification of rheumatic skin diseases with systemic implications and consistency in designing and executing therapeutic trials will be enhanced. This review will provide a compilation of updates on epidemiology, pathology, evaluation, and classification with a predominant focus on therapeutics, reflecting the growth is this area.

摘要

在理解自身免疫性疾病（包括红斑狼疮、皮肌炎和硬皮病）发病机制方面的最新进展，使得对这些疾病的分类得以重新梳理。有了这些新的分层方法，将有助于早期识别具有全身影响的风湿性皮肤病，并在设计和实施治疗试验时保持一致性。本综述将汇总流行病学、病理学、评估和分类方面的最新进展，重点关注治疗方法，以反映该领域的发展情况。