阿奇霉素与阿莫西林-克拉维酸治疗儿童急性鼻窦炎的对比研究
Azythromicin versus amoxicillin-clavulanate in the treatment of acute sinusitis in children.
作者信息
Alagić-Smailbegović Jasminka, Saracević Ediba, Sutalo Kamenko
机构信息
ENT Clinic, University of Sarajevo Clinics Center, Bolnicka 25, 71000 Sarajevo, Bosnia and Herzegovina.
出版信息
Bosn J Basic Med Sci. 2006 Nov;6(4):76-8. doi: 10.17305/bjbms.2006.3127.
In this prospective study we compared the efficiency of azithromycin and amoxicillin-clavulanate in treatment of acute sinusitis in children. Seventy patients were included in the age between 5 and 15 years. Beside ENT and pediatricians examination, nasal and throat smear on culture and antibiogram is taken from all the patients, as well as, X-ray of paranasal sinuses and laboratory findings, followed by check-up of nasal and throat smear and X-ray of paranasal sinuses. Azithromycin in single daily dose of 10 mg/kg during three days showed same efficiency as amoxicillin-clavulanate given three times per day in dose of 45 mg/kg during ten days.
在这项前瞻性研究中，我们比较了阿奇霉素和阿莫西林-克拉维酸盐治疗儿童急性鼻窦炎的疗效。纳入了70名年龄在5至15岁之间的患者。除了耳鼻喉科医生和儿科医生的检查外，还对所有患者进行了鼻腔和咽喉涂片培养及药敏试验，以及鼻窦X光检查和实验室检查，随后复查鼻腔和咽喉涂片以及鼻窦X光检查。阿奇霉素每日单剂量10mg/kg，连用三天，其疗效与阿莫西林-克拉维酸盐每日三次、每次45mg/kg、连用十天相同。
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