串联施陶丁格-氮杂维蒂希介导的环扩展：快速获得新型异法戈明-四羟基氮杂环庚烷杂化物
Tandem Staudinger-azaWittig mediated ring expansion: rapid access to new isofagomine-tetrahydroxyazepane hybrids.
作者信息
Li Hongqing, Zhang Yongmin, Vogel Pierre, Sinaÿ Pierre, Blériot Yves
机构信息
Ecole Normale Supérieure, Département de Chimie, UMR 8642, Université Pierre et Marie Curie-Paris 6, 75005 Paris, France.
出版信息
Chem Commun (Camb). 2007 Jan 14(2):183-5. doi: 10.1039/b610377d. Epub 2006 Oct 24.
DOI:10.1039/b610377d
PMID:17180240
Abstract
New seven-membered iminosugars with potent and selective inhibition towards glycosidases have been prepared as 1-N-iminosugar homologues via a tandem Staudinger-azaWittig mediated ring expansion.
摘要
通过串联施陶丁格-氮杂维蒂希介导的扩环反应，已制备出对糖苷酶具有强效和选择性抑制作用的新型七元亚氨基糖，作为1-N-亚氨基糖同系物。
Zotero 插件